Therapeutic drug monitoring of tacrolimus-personalized therapy: second consensus report

M Brunet, T Van Gelder, A Åsberg… - Therapeutic drug …, 2019 - journals.lww.com
Ten years ago, a consensus report on the optimization of tacrolimus was published in this
journal. In 2017, the Immunosuppressive Drugs Scientific Committee of the International …

[HTML][HTML] Allorecognition and the spectrum of kidney transplant rejection

J Callemeyn, B Lamarthée, A Koenig, P Koshy… - Kidney International, 2022 - Elsevier
Detection of mismatched human leukocyte antigens by adaptive immune cells is considered
as the main cause of transplant rejection, leading to either T-cell mediated rejection or …

[HTML][HTML] The Banff 2015 kidney meeting report: current challenges in rejection classification and prospects for adopting molecular pathology

A Loupy, M Haas, K Solez, L Racusen, D Glotz… - American journal of …, 2017 - Elsevier
The XIII Banff meeting, held in conjunction the Canadian Society of Transplantation in
Vancouver, Canada, reviewed the clinical impact of updates of C4d-negative antibody …

[HTML][HTML] Recommended treatment for antibody-mediated rejection after kidney transplantation: the 2019 expert consensus from the transplantion society working …

CA Schinstock, RB Mannon, K Budde, AS Chong… - …, 2020 - journals.lww.com
This meeting was organized by The Transplantation Society with the assistance of an
unconditional education grant from CSL Behring. CSL Behring had no involvement in the …

Single-cell transcriptomics of a human kidney allograft biopsy specimen defines a diverse inflammatory response

H Wu, AF Malone, EL Donnelly, Y Kirita… - Journal of the …, 2018 - journals.lww.com
Background Single-cell genomics techniques are revolutionizing our ability to characterize
complex tissues. By contrast, the techniques used to analyze renal biopsy specimens have …

Liquid biopsies: donor-derived cell-free DNA for the detection of kidney allograft injury

M Oellerich, K Sherwood, P Keown, E Schütz… - Nature Reviews …, 2021 - nature.com
In kidney transplantation, the use of minimally invasive damage biomarkers that are more
sensitive and specific than plasma creatinine will be crucial to enable early, actionable …

Complement-binding anti-HLA antibodies and kidney-allograft survival

A Loupy, C Lefaucheur, D Vernerey… - … England Journal of …, 2013 - Mass Medical Soc
Background Anti-HLA antibodies hamper successful transplantation, and activation of the
complement cascade is involved in antibody-mediated rejection. We investigated whether …

Prediction system for risk of allograft loss in patients receiving kidney transplants: international derivation and validation study

A Loupy, O Aubert, BJ Orandi, M Naesens, Y Bouatou… - Bmj, 2019 - bmj.com
Objective To develop and validate an integrative system to predict long term kidney allograft
failure. Design International cohort study. Setting Three cohorts including kidney transplant …

[HTML][HTML] Assessment of tocilizumab (anti–interleukin-6 receptor monoclonal) as a potential treatment for chronic antibody-mediated rejection and transplant …

J Choi, O Aubert, A Vo, A Loupy, M Haas… - American Journal of …, 2017 - Elsevier
Extending the functional integrity of renal allografts is the primary goal of transplant
medicine. The development of donor-specific antibodies (DSAs) posttransplantation leads to …

Practical recommendations for long-term management of modifiable risks in kidney and liver transplant recipients: a guidance report and clinical checklist by the …

JM Neuberger, WO Bechstein, DRJ Kuypers… - …, 2017 - journals.lww.com
Short-term patient and graft outcomes continue to improve after kidney and liver
transplantation, with 1-year survival rates over 80%; however, improving longer-term …