The role of Nrf2 in neural stem/progenitors cells: From maintaining stemness and self-renewal to promoting differentiation capability and facilitating therapeutic …
Neurodegenerative diseases (NDs) cause progressive loss of neurons in nervous system.
NDs are categorized as acute NDs such as stroke and head injury, besides chronic NDs …
NDs are categorized as acute NDs such as stroke and head injury, besides chronic NDs …
Neural stem cell therapy for subacute and chronic ischemic stroke
AC Boese, QSE Le, D Pham, MH Hamblin… - Stem cell research & …, 2018 - Springer
Neural stem cells (NSCs) play vital roles in brain homeostasis and exhibit a broad repertoire
of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a …
of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a …
A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke
The therapeutic efficacy of stem cells transplanted into an ischaemic brain depends primarily
on the responses of the neurovascular unit. Here, we report the development and …
on the responses of the neurovascular unit. Here, we report the development and …
Stem cells in human neurodegenerative disorders—time for clinical translation?
O Lindvall, Z Kokaia - The Journal of clinical investigation, 2010 - Am Soc Clin Investig
Stem cell–based approaches have received much hype as potential treatments for
neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in …
neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in …
Current progress in the derivation and therapeutic application of neural stem cells
Y Tang, P Yu, L Cheng - Cell death & disease, 2017 - nature.com
Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on
NSC transplantation is a promising tool for the treatment of nervous system diseases …
NSC transplantation is a promising tool for the treatment of nervous system diseases …
Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain
Reprogramming of adult human somatic cells to induced pluripotent stem cells (iPSCs) is a
novel approach to produce patient-specific cells for autologous transplantation. Whether …
novel approach to produce patient-specific cells for autologous transplantation. Whether …
Neural stem cell therapies and hypoxic-ischemic brain injury
Hypoxic-ischemic brain injury is a significant cause of morbidity and mortality in the adult as
well as in the neonate. Extensive pre-clinical studies have shown promising therapeutic …
well as in the neonate. Extensive pre-clinical studies have shown promising therapeutic …
Stem cell‐based therapies for ischemic stroke
L Hao, Z Zou, H Tian, Y Zhang… - BioMed research …, 2014 - Wiley Online Library
In recent years, stem cell‐based approaches have attracted more attention from scientists
and clinicians due to their possible therapeutical effect on stroke. Animal studies have …
and clinicians due to their possible therapeutical effect on stroke. Animal studies have …
Cartilage repair using hyaluronan hydrogel-encapsulated human embryonic stem cell-derived chondrogenic cells
Human embryonic stem cells (hESCs) have the potential to offer a virtually unlimited source
of chondrogenic cells for use in cartilage repair and regeneration. We have recently shown …
of chondrogenic cells for use in cartilage repair and regeneration. We have recently shown …
Stem cell transplantation therapy for multifaceted therapeutic benefits after stroke
One of the exciting advances in modern medicine and life science is cell-based
neurovascular regeneration of damaged brain tissues and repair of neuronal structures. The …
neurovascular regeneration of damaged brain tissues and repair of neuronal structures. The …