The role of Nrf2 in neural stem/progenitors cells: From maintaining stemness and self-renewal to promoting differentiation capability and facilitating therapeutic …

H Kahroba, B Ramezani, H Maadi, MR Sadeghi… - Ageing research …, 2021 - Elsevier
Neurodegenerative diseases (NDs) cause progressive loss of neurons in nervous system.
NDs are categorized as acute NDs such as stroke and head injury, besides chronic NDs …

Neural stem cell therapy for subacute and chronic ischemic stroke

AC Boese, QSE Le, D Pham, MH Hamblin… - Stem cell research & …, 2018 - Springer
Neural stem cells (NSCs) play vital roles in brain homeostasis and exhibit a broad repertoire
of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a …

A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke

Z Lyu, J Park, KM Kim, HJ Jin, H Wu… - Nature biomedical …, 2021 - nature.com
The therapeutic efficacy of stem cells transplanted into an ischaemic brain depends primarily
on the responses of the neurovascular unit. Here, we report the development and …

Stem cells in human neurodegenerative disorders—time for clinical translation?

O Lindvall, Z Kokaia - The Journal of clinical investigation, 2010 - Am Soc Clin Investig
Stem cell–based approaches have received much hype as potential treatments for
neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in …

Current progress in the derivation and therapeutic application of neural stem cells

Y Tang, P Yu, L Cheng - Cell death & disease, 2017 - nature.com
Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on
NSC transplantation is a promising tool for the treatment of nervous system diseases …

Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain

K Oki, J Tatarishvili, J Wood, P Koch, S Wattananit… - Stem …, 2012 - academic.oup.com
Reprogramming of adult human somatic cells to induced pluripotent stem cells (iPSCs) is a
novel approach to produce patient-specific cells for autologous transplantation. Whether …

Neural stem cell therapies and hypoxic-ischemic brain injury

L Huang, L Zhang - Progress in neurobiology, 2019 - Elsevier
Hypoxic-ischemic brain injury is a significant cause of morbidity and mortality in the adult as
well as in the neonate. Extensive pre-clinical studies have shown promising therapeutic …

Stem cell‐based therapies for ischemic stroke

L Hao, Z Zou, H Tian, Y Zhang… - BioMed research …, 2014 - Wiley Online Library
In recent years, stem cell‐based approaches have attracted more attention from scientists
and clinicians due to their possible therapeutical effect on stroke. Animal studies have …

Cartilage repair using hyaluronan hydrogel-encapsulated human embryonic stem cell-derived chondrogenic cells

WS Toh, EH Lee, XM Guo, JKY Chan, CH Yeow… - Biomaterials, 2010 - Elsevier
Human embryonic stem cells (hESCs) have the potential to offer a virtually unlimited source
of chondrogenic cells for use in cartilage repair and regeneration. We have recently shown …

Stem cell transplantation therapy for multifaceted therapeutic benefits after stroke

L Wei, ZZ Wei, MQ Jiang, O Mohamad, SP Yu - Progress in neurobiology, 2017 - Elsevier
One of the exciting advances in modern medicine and life science is cell-based
neurovascular regeneration of damaged brain tissues and repair of neuronal structures. The …