On the 400th anniversary of Harvey's Lumleian lectures, this review focuses on
“hemodynamic” forces associated with the movement of blood through arteries in humans …

While epigenetic modifications of DNA and histones play main roles in gene transcription
regulation, recently discovered post-transcriptional RNA modifications, known as …

Beige fat plays key roles in the regulation of systemic energy homeostasis; however,
detailed mechanisms and safe strategy for its activation remain elusive. In this study, we …

Key points A recent 30 year prospective study showed that lifelong sauna use reduces
cardiovascular‐related and all‐cause mortality; however, the specific cardiovascular …

A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​—The Wall Street Journal A
paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of …

Sauna bathing, an activity that has been a tradition in Finland for thousands of years and
mainly used for the purposes of pleasure and relaxation, is becoming increasingly popular …

Background there are no previous studies linking repeated heat exposure of sauna and the
risk of memory diseases. We aimed to investigate whether frequency of sauna bathing is …

Sauna use, sometimes referred to as “sauna bathing,” is characterized by short-term passive
exposure to high temperatures, typically ranging from 45° C to 100° C (113° F to 212° F) …

Cardiovascular diseases (CVD) are the leading cause of death worldwide, and novel
therapies are drastically needed to prevent or delay the onset of CVD to reduce the societal …

Introduction. Many health benefits are claimed by individuals and facilities promoting sauna
bathing; however the medical evidence to support these claims is not well established. This …