An investigation of binding interactions of tumor-targeted peptide conjugated polyphenols with the kinase domain of ephrin B4 and B2 receptors

SM Mitchell, RM Heise, ME Murray, DJ Lambo… - Molecular Diversity, 2024 - Springer
Recent studies have shown that Ephrin receptors may be upregulated in several types of
cancers including breast, ovarian and endometrial cancers, making them a target for drug …

The Effects of Deoxyelephantopin on the Akt/mTOR/P70S6K Signaling Pathway in MCF-7 Breast Carcinoma Cells In Vitro

WFWM Fazil, A Amanah… - Journal of …, 2022 - journals.sagepub.com
Objective To determine the effects of deoxyelephantopin on mTOR and its related target
molecules (Akt/mTOR/P70S6K) in the ER-positive breast cancer cell line. Materials and …

Modeling, Synthesis and Characterization of Phospho–Penta–Peptide derived from PKA RII Sub Unit: A Candidate Substrate for CaN Assay

SR Bulbule, P Aravind, N Hemalatha… - International Journal of …, 2019 - Springer
Calcineurin (CaN) plays an important role in many pathological conditions like cancer,
metabolic aberrations and neurodegenerative disorders. Till date contemporary methods to …