Enzymatic Characterization of the Isocitrate Dehydrogenase with Dual Coenzyme Specificity from the Marine Bacterium Umbonibacter marinipuiceus
M Bian, J Zhao, W Xu, X Han, X Chen, P Wang… - International Journal of …, 2023 - mdpi.com
Isocitrate dehydrogenase (IDH) can be divided into NAD+-dependent and NADP+-
dependent types based on the coenzyme specificity. It is worth noting that some IDHs exhibit …
dependent types based on the coenzyme specificity. It is worth noting that some IDHs exhibit …
Novel Type II and Monomeric NAD+ Specific Isocitrate Dehydrogenases: Phylogenetic Affinity, Enzymatic Characterization and Evolutionary Implication
P Wang, C Lv, G Zhu - Scientific reports, 2015 - nature.com
NAD+ use is an ancestral trait of isocitrate dehydrogenase (IDH) and the NADP+ phenotype
arose through evolution as an ancient adaptation event. However, no NAD+-specific IDHs …
arose through evolution as an ancient adaptation event. However, no NAD+-specific IDHs …
The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer‐Like Pathological Changes In Vitro
P Liu, X Chen, H Zhou, L Wang, Z Zhang… - Oxidative medicine …, 2018 - Wiley Online Library
Alzheimer's disease (AD), the most common neurodegenerative disease, has no effective
treatment. Dauricine (DAU), a benzyl tetrahydroisoquinoline alkaloid isolated from the root of …
treatment. Dauricine (DAU), a benzyl tetrahydroisoquinoline alkaloid isolated from the root of …
Biochemical and molecular characterization of the isocitrate dehydrogenase with dual coenzyme specificity from the obligate methylotroph Methylobacillus Flagellatus
AY Romkina, MY Kiriukhin - Plos one, 2017 - journals.plos.org
The isocitrate dehydrogenase (Mf IDH) with unique double coenzyme specificity from
Methylobacillus flagellatus was purified and characterized, and its gene was cloned and …
Methylobacillus flagellatus was purified and characterized, and its gene was cloned and …
Physiological Regulation of Isocitrate Dehydrogenase and the Role of 2-Oxoglutarate in Prochlorococcus sp. Strain PCC 9511
MA Domínguez-Martín, A Lopez-Lozano, J Diez… - PLoS …, 2014 - journals.plos.org
The enzyme isocitrate dehydrogenase (ICDH; EC 1.1. 1.42) catalyzes the oxidative
decarboxylation of isocitrate, to produce 2-oxoglutarate. The incompleteness of the …
decarboxylation of isocitrate, to produce 2-oxoglutarate. The incompleteness of the …
Purification and characterization of isocitrate dehydrogenase from Mortierella alpina
X Wang, X Tang, H Chen, H Zhang, YQ Chen… - Process …, 2022 - Elsevier
Isocitrate dehydrogenase (IDH) in oleaginous microorganisms plays an essential role in fatty
acid synthesis. We expressed and purified an IDH isozyme from the oleaginous fungus …
acid synthesis. We expressed and purified an IDH isozyme from the oleaginous fungus …
Expression and Characterization of Monomeric Recombinant Isocitrate Dehydrogenases from Corynebacterium glutamicum and Azotobacter vinelandii for NADPH …
The enzymatic transformation of various chemicals, especially using NADPH-dependent
hydroxylase, into more soluble and/or high value-added products has steadily garnered …
hydroxylase, into more soluble and/or high value-added products has steadily garnered …
Biochemical and phylogenetic characterization of a monomeric isocitrate dehydrogenase from a marine methanogenic archaeon Methanococcoides methylutens
P Wang, Y Wang, X Guo, S Huang, G Zhu - Extremophiles, 2020 - Springer
Monomeric isocitrate dehydrogenase (IDH) stands for a separated subgroup among IDH
protein family. Up to now, all reported monomeric IDHs are from prokaryotes. Here, a …
protein family. Up to now, all reported monomeric IDHs are from prokaryotes. Here, a …
Crystal structure studies of NADP+ dependent isocitrate dehydrogenase from Thermus thermophilus exhibiting a novel terminal domain
NADP+ dependent isocitrate dehydrogenase (IDH) is an enzyme catalyzing oxidative
decarboxylation of isocitrate into oxalosuccinate (intermediate) and finally the product α …
decarboxylation of isocitrate into oxalosuccinate (intermediate) and finally the product α …
Acidophilic Micrarchaeon Seems to Maintain a Slightly Alkaline Cytosolic pH
D Winkler, S Gfrerer, J Gescher - bioRxiv, 2021 - biorxiv.org
Despite several discoveries in recent years, the physiology of acidophilic Micrarchaeota
remains largely enigmatic.“Candidatus Micrarchaeum harzensis A_DKE”, for example …
remains largely enigmatic.“Candidatus Micrarchaeum harzensis A_DKE”, for example …