Chronic Venous Disease (CVD) refers to several pathological and hemodynamic alterations
of the veins of lower limbs causing a wide range of symptoms and signs with a high …

Background Varicose veins, a common problem with effects on quality of life, account for a
significant cost burden on the health care system. Despite their prevalence, the …

From developmental stages until adulthood, the circulatory system remodels in response to
changes in blood flow in order to maintain vascular homeostasis. Remodeling processes …

Chronic venous diseases, including varicose veins, are characterized by hemodynamic
disturbances due to valve defects, venous insufficiency, and orthostatism. Veins are …

Background Cerebral arteriovenous malformations (cAVM) are a significant cause of
intracranial hemorrhagic stroke and brain damage. The arteriovenous junctions in AVM …

The pesticide fipronil is widely dispersed in aquatic environments and frequently detected in
the general population. Although the adverse effects on embryonic growth by fipronil …

Varicose veins are among the most common disorders of the vascular system; however, the
pathogenesis of varicose veins remains unclear. The present study aimed to investigate the …

Objectives Chronic venous disease (CVeD) is a multifactorial and debilitating condition that
has a high prevalence in Western countries and an important associated socioeconomic …

Chronic venous disease (CVD) is a very common clinical syndrome affecting up to 80% of
the western world. CVD involves primarily peripheral vein circulation of lower limbs with the …

Endothelium of blood vessels is continuously exposed to various hemodynamic forces. Flow-
mediated epigenetic plasticity regulates vascular endothelial function. Recent studies have …