The outbreak of SARS‐CoV‐2 Omicron lineages, immune escape, and vaccine effectivity

Y Zhou, H Zhi, Y Teng - Journal of medical virology, 2023 - Wiley Online Library
As of November 2021, several SARS‐CoV‐2 variants appeared and became dominant
epidemic strains in many countries, including five variants of concern (VOCs) Alpha, Beta …

[HTML][HTML] Hybrid immunity to SARS-CoV-2 from infection and vaccination—evidence synthesis and implications for new COVID-19 vaccines

JR Spinardi, A Srivastava - Biomedicines, 2023 - mdpi.com
COVID-19 has taken a severe toll on the global population through infections,
hospitalizations, and deaths. Elucidating SARS-CoV-2 infection-derived immunity has led to …

A spike-trimer protein-based tetravalent COVID-19 vaccine elicits enhanced breadth of neutralization against SARS-CoV-2 Omicron subvariants and other variants

R Wang, H Huang, C Yu, C Sun, J Ma, D Kong… - Science China Life …, 2023 - Springer
Multivalent vaccines combining crucial mutations from phylogenetically divergent variants
could be an effective approach to defend against existing and future SARS-CoV-2 variants …

Neutralization of Omicron sublineages and Deltacron SARS-CoV-2 by three doses of BNT162b2 vaccine or BA. 1 infection

C Kurhade, J Zou, H Xia, M Liu, Q Yang… - Emerging microbes & …, 2022 - Taylor & Francis
ABSTRACT Distinct SARS-CoV-2 Omicron sublineages have evolved showing increased
fitness and immune evasion than the original Omicron variant BA. 1. Here, we report the …

[HTML][HTML] Dispersal patterns and influence of air travel during the global expansion of SARS-CoV-2 variants of concern

H Tegally, E Wilkinson, JLH Tsui, M Moir, D Martin… - Cell, 2023 - cell.com
Summary The Alpha, Beta, and Gamma SARS-CoV-2 variants of concern (VOCs) co-
circulated globally during 2020 and 2021, fueling waves of infections. They were displaced …

[HTML][HTML] Different neutralization profiles after primary SARS-CoV-2 Omicron BA. 1 and BA. 2 infections

I Medits, DN Springer, M Graninger, JV Camp… - Frontiers in …, 2022 - frontiersin.org
Background and Methods The SARS-CoV-2 (severe acute respiratory syndrome
coronavirus 2) Omicron (B. 1.1. 529) variant is the antigenically most distinct variant to date …

An antibody that neutralizes SARS-CoV-1 and SARS-CoV-2 by binding to a conserved spike epitope outside the receptor binding motif

Y Fang, P Sun, X Xie, M Du, F Du, J Ye… - Science …, 2022 - science.org
The rapid evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
such as the Omicron variants that are highly transmissible and immune evasive …

[HTML][HTML] Omicron BA. 2 lineage, the “stealth” variant: is it truly a silent epidemic? A literature review

G Tiecco, S Storti, S Arsuffi, M Degli Antoni… - International Journal of …, 2022 - mdpi.com
The epidemic curve of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
silently rising again. Worldwide, the dominant SARS-CoV-2 variant of concern (VOC) is …

Reverse genetic systems of SARS-CoV-2 for antiviral research

C Kurhade, X Xie, PY Shi - Antiviral research, 2023 - Elsevier
Reverse genetic systems are widely used to engineer recombinant viruses with desired
mutations. In response to the COVID-19 pandemic, four types of reverse genetic systems …

Cross-neutralization and viral fitness of SARS-CoV-2 Omicron sublineages

H Xia, J Yeung, B Kalveram, CJ Bills… - Emerging microbes & …, 2023 - Taylor & Francis
The rapid evolution of SARS-CoV-2 Omicron sublineages mandates a better understanding
of viral replication and cross-neutralization among these sublineages. Here we used K18 …