Accumulating evidence shows that cellular and acellular components in tumor
microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and …

The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …

Because of the compartmentalization of disciplines that shaped the academic landscape of
biology and biomedical sciences in the past, physiological systems have long been studied …

The peripheral autonomic nervous system (ANS) is known to regulate gene expression in
primary tumours and their surrounding microenvironment. Activation of the sympathetic …

Evidence suggests that the perioperative period and the excision of the primary tumour can
promote the development of metastases—the main cause of cancer-related mortality. This …

The sympathetic nervous system has a major role in the brain-immune cross-talk, but few
information exist on the sympathoadrenergic regulation of innate immune system. The aim of …

Neurotransmitters are conventionally viewed as nerve-secreted substances that mediate the
stimulatory or inhibitory neuronal functions through binding to their respective receptors. In …

Beta-adrenergic signaling has been found to regulate multiple cellular processes that
contribute to the initiation and progression of cancer, including inflammation, angiogenesis …

Purpose: Translational studies suggest that excess perioperative release of catecholamines
and prostaglandins may facilitate metastasis and reduce disease-free survival. This trial …

Surgery is unanimously regarded as the primary strategy to cure solid tumors in the early
stages but is not always used in advanced cases. However, tumor surgery must be carefully …