Dimethyl sulfoxide: yesterday's solvent, today's reagent

Z Tashrifi, MM Khanaposhtani… - Advanced Synthesis …, 2020 - Wiley Online Library
Dimethyl sulfoxide (DMSO) has had a long history of use as a polar solvent and active
pharmaceutical ingredient in the past decades. However, in this decade DMSO has attracted …

Recent advances in the use of dimethyl sulfoxide as a synthon in organic chemistry

H Lu, Z Tong, L Peng, Z Wang, SF Yin… - Topics in Current …, 2022 - Springer
Dimethyl sulfoxide (DMSO), as extremely important aprotic polar solvent and reaction
medium, has attracted widespread attention from chemists in recent years due to its wide …

Modification of Pyrrolo[2,1-a]isoquinolines and Pyrrolo[1,2-a]quinolines with Ammonium Acetate and Dimethyl Sulfoxide via Methylthiomethylation

JQ Li, XH Chen, HL Cui - The Journal of Organic Chemistry, 2022 - ACS Publications
An efficient methylthiomethylation of pyrroloisoquinolines and pyrroloquinolines has been
reached by the use of ammonium acetate and dimethyl sulfoxide. Methylthiomethylated …

Redox‐Divergent Construction of (Dihydro) thiophenes with DMSO

H Liu, GC He, CY Zhao, XX Zhang, DW Ji… - Angewandte …, 2021 - Wiley Online Library
Thiophene‐based rings are one of the most widely used building blocks for the synthesis of
sulfur‐containing molecules. Inspired by the redox diversity of these features in nature, we …

Formylation and Bromination of Pyrrolo[2,1-a]isoquinoline Derivatives with Bromoisobutyrate and Dimethyl Sulfoxide

JQ Li, HL Tan, DD Ma, XX Zhu… - The Journal of Organic …, 2021 - ACS Publications
We have developed an efficient formylation of pyrroloisoquinolines using bromoisobutyrate
and dimethyl sulfoxide as carbonyl reagent. Various formylated pyrroloisoquinolines could …

[3+ 1+ 1+ 1] annulation to the pyridine structure in quinoline molecules based on DMSO as a nonadjacent dual-methine synthon: simple synthesis of 3-arylquinolines …

T Yang, H Li, Z Nie, M Su, W Luo, Q Liu… - The Journal of Organic …, 2022 - ACS Publications
A [3+ 1+ 1+ 1] annulation of arylamines, arylaldehydes, and dimethyl sulfoxide (DMSO) to
the pyridine structure in quinolines using DMSO as a nonadjacent dual-methine (═ CH−) …

NH4OAc/DMSO-Promoted Benzylation of Pyrrolo[2,1-a]isoquinolines

XH Chen, T Lhazom, HL Cui - The Journal of Organic Chemistry, 2023 - ACS Publications
Benzylation of pyrrolo [2, 1-a] isoquinoline derivatives has been realized with various
phenols by the use of ammonium acetate as a promoter (20 examples, up to 84% yield) …

Modification of Pyrrolo[2,1-a]isoquinolines and Polysubstituted Pyrroles via Methylenation with Acetyl Chloride and Dimethylsulfoxide

WZ Li, W Zhang, XH Chen, ZD Wang… - The Journal of Organic …, 2022 - ACS Publications
A convenient synthesis of methylene-bridged pyrrolo [2, 1-a] isoquinolines has been
developed. Treatment of pyrroloisoquinolines with acetyl chloride and dimethylsulfoxide …

Oxone-DMSO Triggered Methylene Insertion and C(sp2)−C(sp3)-H−C(sp2) Bond Formation to Access Functional Bis-Heterocycles

J Kour, V Venkateswarlu, PK Verma… - The Journal of …, 2020 - ACS Publications
Metal-free insertion of a methylene group was achieved for the construction of a new C (sp2)–
C (sp3)-H–C (sp2) bond in order to prepare novel bis-heterocyclic scaffolds. The complete …

Convenient Preparation of N-Acylbenzoxazines from Phenols, Nitriles, and DMSO Initiated by a Catalytic Amount of (COCl)2

H Wang, Z Xi, S Huang, R Ding, Y Gao… - The Journal of …, 2021 - ACS Publications
A convenient preparation method of N-acylbenzoxazines has been developed, in which
phenols react with nitriles and dimethyl sulfoxide (DMSO) in the presence of a catalytic …