Using neuroscience to help understand fear and anxiety: a two-system framework

JE LeDoux, DS Pine - American journal of psychiatry, 2016 - Am Psychiatric Assoc
Tremendous progress has been made in basic neuroscience in recent decades. One area
that has been especially successful is research on how the brain detects and responds to …

Emotion regulation as a transdiagnostic factor in the development of internalizing and externalizing psychopathology: Current and future directions

A Aldao, DG Gee, A De Los Reyes… - Development and …, 2016 - cambridge.org
In response to rapidly growing rates of comorbidity among psychiatric disorders, clinical
scientists have become interested in identifying transdiagnostic processes that can help …

[HTML][HTML] Inflammation in fear-and anxiety-based disorders: PTSD, GAD, and beyond

V Michopoulos, A Powers, CF Gillespie… - …, 2017 - nature.com
The study of inflammation in fear-and anxiety-based disorders has gained interest as
growing literature indicates that pro-inflammatory markers can directly modulate affective …

[HTML][HTML] Social brain, social dysfunction and social withdrawal

S Porcelli, N Van Der Wee, S van der Werff… - Neuroscience & …, 2019 - Elsevier
The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

Development of the emotional brain

BJ Casey, AS Heller, DG Gee, AO Cohen - Neuroscience letters, 2019 - Elsevier
In this article, we highlight the importance of dynamic reorganization of neural circuitry
during adolescence, as it relates to the development of emotion reactivity and regulation. We …

The etiology of social anxiety disorder: An evidence-based model

SH Spence, RM Rapee - Behaviour research and therapy, 2016 - Elsevier
The current paper presents an update to the model of social anxiety disorder (social phobia)
published by Rapee and Spence (2004). It evaluates the research over the intervening 11 …

Respiratory sinus arrhythmia: A transdiagnostic biomarker of emotion dysregulation and psychopathology

TP Beauchaine - Current opinion in psychology, 2015 - Elsevier
Highlights•RSA is a valid and reliable biomarker of emotion regulation capacity in
humans.•Low tonic RSA and excessive RSA reactivity to emotion evocation mark PFC …

How does mindfulness meditation work? Proposing mechanisms of action from a conceptual and neural perspective

BK Hölzel, SW Lazar, T Gard… - Perspectives on …, 2011 - journals.sagepub.com
Cultivation of mindfulness, the nonjudgmental awareness of experiences in the present
moment, produces beneficial effects on well-being and ameliorates psychiatric and stress …

Future directions in emotion dysregulation and youth psychopathology

TP Beauchaine - Journal of Clinical Child & Adolescent …, 2015 - Taylor & Francis
This article reviews central nervous system substrates and autonomic correlates of emotion
dysregulation and offers several suggestions for future research. Studies conducted in the …

Irritability in youths: A translational model

MA Brotman, K Kircanski, A Stringaris… - American Journal of …, 2017 - Am Psychiatric Assoc
Although irritability is among the most common reasons that children and adolescents are
brought for psychiatric care, there are few effective treatments. Developmentally sensitive …