Decellularized Extracellular Matrix as an In Vitro Model to Study the Comprehensive Roles of the ECM in Stem Cell Differentiation

T Hoshiba, G Chen, C Endo, H Maruyama… - Stem cells …, 2016 - Wiley Online Library
Stem cells are a promising cell source for regenerative medicine. Stem cell differentiation
must be regulated for applications in regenerative medicine. Stem cells are surrounded by …

[HTML][HTML] The extracellular matrix of hematopoietic stem cell niches

C Lee-Thedieck, P Schertl, G Klein - Advanced Drug Delivery Reviews, 2022 - Elsevier
Hematopoietic stem cells (HSCs) are the life-long source of all types of blood cells. Their
function is controlled by their direct microenvironment, the HSC niche in the bone marrow …

Preventing brain injury in the preterm infant—current controversies and potential therapies

N Yates, AJ Gunn, L Bennet, SK Dhillon… - International journal of …, 2021 - mdpi.com
Preterm birth is associated with a high risk of morbidity and mortality including brain damage
and cerebral palsy. The development of brain injury in the preterm infant may be influenced …

[HTML][HTML] Current insights into the bone marrow niche: From biology in vivo to bioengineering ex vivo

Y Xiao, CAS McGuinness, WS Doherty-Boyd… - Biomaterials, 2022 - Elsevier
Hematopoietic stem cells (HSCs) are fundamental to the generation of the body's blood and
immune cells. They reside primarily within the bone marrow (BM) niche microenvironment …

Recent advances in organoid engineering: A comprehensive review

JM Unagolla, AC Jayasuriya - Applied materials today, 2022 - Elsevier
Organoid, a 3D structure derived from various cell sources including progenitor and
differentiated cells that self-organize through cell-cell and cell-matrix interactions to …

Polycaprolactone/graphene oxide/acellular matrix nanofibrous scaffolds with antioxidant and promyelinating features for the treatment of peripheral demyelinating …

A Nagarajan, N Rizwana, M Abraham, M Bhat… - Journal of Materials …, 2023 - Springer
Peripheral demyelinating diseases entail damage to axons and Schwann cells in the
peripheral nervous system. Because of poor prognosis and lack of a cure, this group of …

Stem cell therapy to protect and repair the developing brain: a review of mechanisms of action of cord blood and amnion epithelial derived cells

M Castillo-Melendez, T Yawno, G Jenkin… - Frontiers in …, 2013 - frontiersin.org
In the research, clinical, and wider community there is great interest in the use of stem cells
to reduce the progression, or indeed repair brain injury. Perinatal brain injury may result …

Collagen type-I leads to in vivo matrix mineralization and secondary stabilization of Mg–Zr–Ca alloy implants

D Mushahary, C Wen, JM Kumar, J Lin… - Colloids and Surfaces B …, 2014 - Elsevier
Biodegradable magnesium–zirconia–calcium (Mg–Zr–Ca) alloy implants were coated with
Collagen type-I (Coll-I) and assessed for their rate and efficacy of bone mineralization and …

Film Thickness Determines Cell Growth and Cell Sheet Detachment from Spin-Coated Poly(N-Isopropylacrylamide) Substrates

NA Dzhoyashvili, K Thompson… - … Applied Materials & …, 2016 - ACS Publications
Poly (N-isopropylacrylamide)(pNIPAm) is widely used to fabricate thermoresponsive
surfaces for cell sheet detachment. Many complex and expensive techniques have been …

Constructing three-dimensional microenvironments using engineered biomaterials for hematopoietic stem cell expansion

G Ingavle, A Vaidya, V Kale - Tissue Engineering Part B: Reviews, 2019 - liebertpub.com
In a native bone marrow tissue microenvironment, mesenchymal stem/stromal cells form an
important constituent of the stem cell niche, which is composed of extracellular matrix (ECM) …