Revisiting the rules of life for viruses of microorganisms

AMS Correa, C Howard-Varona, SR Coy… - Nature Reviews …, 2021 - nature.com
Viruses that infect microbial hosts have traditionally been studied in laboratory settings with
a focus on either obligate lysis or persistent lysogeny. In the environment, these infection …

Regulation of prophage induction and lysogenization by phage communication systems

JB Bruce, S Lion, A Buckling, ER Westra, S Gandon - Current Biology, 2021 - cell.com
Many viruses cause both lytic infections, where they release viral particles, and dormant
infections, where they await future opportunities to reactivate. 1 The benefits of each …

Alternating lysis and lysogeny is a winning strategy in bacteriophages due to Parrondo's paradox

KH Cheong, T Wen, S Benler… - Proceedings of the …, 2022 - National Acad Sciences
Temperate bacteriophages lyse or lysogenize host cells depending on various parameters
of infection, a key one being the ratio of the number of free viruses to the number of host …

When to be temperate: on the fitness benefits of lysis vs. lysogeny

G Li, MH Cortez, J Dushoff, JS Weitz - Virus Evolution, 2020 - academic.oup.com
Bacterial viruses, that is 'bacteriophage'or 'phage', can infect and lyse their bacterial hosts,
releasing new viral progeny. In addition to the lytic pathway, certain bacteriophage (ie …

[HTML][HTML] Appelmans protocol–A directed in vitro evolution enables induction and recombination of prophages with expanded host range

TN Vu, JR Clark, E Jang, R D'Souza, NA Pinto, S Yoo… - Virus Research, 2024 - Elsevier
Infections caused by carbapenem-resistant Acinetobacter baumannii (CRAB) present
significant healthcare challenges due to limited treatment options. Bacteriophage (phage) …

Beyond arbitrium: identification of a second communication system in Bacillus phage phi3T that may regulate host defense mechanisms

C Bernard, Y Li, P Lopez, E Bapteste - The ISME Journal, 2021 - academic.oup.com
The evolutionary stability of temperate bacteriophages at low abundance of susceptible
bacterial hosts lies in the trade-off between the maximization of phage replication, performed …

An Eco-evolutionary Model on Surviving Lysogeny Through Grounding and Accumulation of Prophages

PA Sudhakari, BCM Ramisetty - Microbial Ecology, 2023 - Springer
Temperate phages integrate into the bacterial genomes propagating along with the bacterial
genomes. Multiple phage elements, representing diverse prophages, are present in most …

Evolution along the parasitism-mutualism continuum determines the genetic repertoire of prophages

A Khan, AR Burmeister, LM Wahl - PLoS Computational Biology, 2020 - journals.plos.org
Integrated into their bacterial hosts' genomes, prophage sequences exhibit a wide diversity
of length and gene content, from highly degraded cryptic sequences to intact, functional …

From bench to keyboard and back again: a brief history of lambda phage modeling

MG Cortes, Y Lin, L Zeng… - Annual review of …, 2021 - annualreviews.org
Cellular decision making is the process whereby cells choose one developmental pathway
from multiple possible ones, either spontaneously or due to environmental stimuli. Examples …

The value of information gathering in phage–bacteria warfare

Y Dahan, NS Wingreen, Y Meir - PNAS nexus, 2024 - academic.oup.com
Phages—viruses that infect bacteria—have evolved over billions of years to overcome
bacterial defenses. Temperate phage, upon infection, can “choose” between two pathways …