Built-in loops allow versatility in domain–domain interactions: lessons from self-interacting domains

E Akiva, Z Itzhaki, H Margalit - Proceedings of the National …, 2008 - National Acad Sciences
Compilations of domain–domain interactions based on solved structures suggest there are
distinct domain pairs that are used repeatedly in different protein contexts to mediate protein …

Conservation of unfavorable sequence motifs that contribute to the chemokine quaternary state

I Kagiampakis, H Jin, S Kim, M Vannucci… - Biochemistry, 2008 - ACS Publications
In the chemokine family, we characterize two examples of evolutionarily conserved
unfavorable sequence motifs that affect quaternary structure. In contrast to the …

[图书][B] Improving the anti-HIV potency of different compounds through synergy and covalent linkage: Dimerization studies of CXCL8

I Kagiampakis - 2010 - search.proquest.com
In the first part of my dissertation we focused on the development of covalently linking
compounds that bind gp120 with those that bind gp41 in order to block HIV fusion. We used …

[PDF][PDF] Detecting Selection in DNA Sequences: Bayesian Modelling and Inference

JM Bernardo, MJ Bayarri, JO Berger, AP Dawid… - Citeseer
Recent developments in Bayesian modelling of DNA sequence data for detecting natural
selection at the amino acid level are presented. This article summarizes and discusses …