The neural crest (NC) is a transient, multipotent and migratory cell population that generates
an astonishingly diverse array of cell types during vertebrate development. These cells …

Objective Traditionally, amniocentesis is performed between 17 and 23 weeks of gestation.
This enables decisions regarding the course of pregnancy to be made before viability. Less …

Congenital upper limb differences are frequently associated with complex syndromes.
Ultrasonography is considered as the first-line diagnostic modality, and fetal MRI can be …

Background: Split-hand/foot malformation type 1 (SHFM1) refers to the group of rare
congenital limb disorders defined by the absence or hypoplasia of the central rays of the …

Variation in fin shape is one of the most prominent features of morphological diversity
among fish. Regulation of fin growth has mainly been studied in zebrafish, and it is not clear …

The split hand/split foot malformation (SHFM) or ectrodactyly is a rare congenital
heterogeneous limb developmental disorder with at least 6 associated loci. It is …

Split hand/foot malformation (SHFM) is a congenital heterogeneous disorder with prominent
limb deficiency. Seven loci have been identified to associate with SHFM, including SHFM1 …

Copy number variation in loss of 7q21 is a genetic disorder characterized by split hand/foot
malformation, hearing loss, developmental delay, myoclonus, dystonia, joint laxity, and …

Comparing gene regulatory patterns between seemingly similar phenotypic traits can
provide important insights on the molecular mechanisms underlying the evolution of those …

Split hand/foot malformation (SHFM) or ectrodactyly is a rare congenital disorder affecting
limb development characterized by clinical and genetic heterogeneity. SHFM is usually …