Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …

There is increasing evidence that both mechanical and biochemical signals play important
roles in development and disease. The development of complex organisms, in particular …

The emergence of Turing structures is of fundamental importance, and designing these
structures and developing their applications have practical effects in chemistry and biology …

The skin is a multilayered organ, equipped with appendages (that is, follicles and glands),
that is critical for regulating body temperature and the retention of bodily fluids, guarding …

Spatially resolved single-cell RNA sequencing (scRNAseq) is a powerful approach for
inferring connections between a cell's identity and its position in a tissue. We recently …

The Turing, or reaction-diffusion (RD), model is one of the best-known theoretical models
used to explain self-regulated pattern formation in the developing animal embryo. Although …

One of the most fundamental questions in biology is that of biological pattern: how do the
structures and shapes of organisms arise? Undoubtedly, the two most influential ideas in …

Wnt signaling is crucial for embryonic development in all animal species studied to date. The
interaction between Wnt proteins and cell surface receptors can result in a variety of …

Morphogenesis emerges from complex multiscale interactions between genetic and
mechanical processes. To understand these processes, the evolution of cell shape …

Our knowledge of the principles by which organ architecture develops through complex
collective cell behaviours is still limited. Recent work has shown that the shape of such …