Globally, 296 million people are infected with hepatitis B virus (HBV), and approximately one
million people die annually from HBV-related causes, including liver cancer. Although there …

At least 250 million people worldwide are chronically infected with HBV, a small
hepatotropic DNA virus that replicates through reverse transcription. Chronic infection …

Human hepatitis B virus (HBV) is the prototype of a family of small DNA viruses that
productively infect hepatocytes, the major cell of the liver, and replicate by reverse …

Background & Aims Hepatitis B virus (HBV) RNA in serum has recently been linked to
efficacy and prognosis of chronic hepatitis B (CHB) treatment. This study explored the …

Chronic infection with hepatitis B virus (HBV) greatly increases the risk for liver cirrhosis and
hepatocellular carcinoma (HCC). HBV isolates worldwide can be divided into ten genotypes …

Hepatitis B virus (HBV) is a para-retrovirus or retroid virus that contains a double-stranded
DNA genome and replicates this DNA via reverse transcription of a RNA pregenome. Viral …

Chronic hepatitis B infection is one of the major etiological causes of liver failure, cirrhosis,
and hepatocellular carcinoma (HCC) worldwide. This condition cannot be completely cured …

Abstract Hepatitis B Virus (HBV) is a small virus whose genome has only four open reading
frames. We argue that the simplicity of the virion correlates with a complexity of functions for …

As obligate intracellular parasites, viruses need a host cell to provide a milieu favorable to
viral replication. Consequently, viruses often adopt mechanisms to subvert host cellular …

The core (capsid) protein of hepatitis B virus (HBV) is the building block of nucleocapsids
where viral DNA reverse transcriptional replication takes place and mediates virus-host cell …