Bioactive peptides and proteins from centipede venoms
Y Han, PM Kamau, R Lai, L Luo - Molecules, 2022 - mdpi.com
Venoms are a complex cocktail of biologically active molecules, including peptides, proteins,
polyamide, and enzymes widely produced by venomous organisms. Through long-term …
polyamide, and enzymes widely produced by venomous organisms. Through long-term …
Centipede venom: a potential source of ion channel modulators
A Luo, A Wang, PM Kamau, R Lai, L Luo - International Journal of …, 2022 - mdpi.com
Centipedes are one of the most ancient and successful living venomous animals. They have
evolved spooky venoms to deter predators or hunt prey, and are widely distributed …
evolved spooky venoms to deter predators or hunt prey, and are widely distributed …
Phylogenetic analyses suggest centipede venom arsenals were repeatedly stocked by horizontal gene transfer
EAB Undheim, RA Jenner - Nature Communications, 2021 - nature.com
Venoms have evolved over a hundred times in animals. Venom toxins are thought to evolve
mostly by recruitment of endogenous proteins with physiological functions. Here we report …
mostly by recruitment of endogenous proteins with physiological functions. Here we report …
Insights into how development and life-history dynamics shape the evolution of venom
Venomous animals are a striking example of the convergent evolution of a complex trait.
These animals have independently evolved an apparatus that synthesizes, stores, and …
These animals have independently evolved an apparatus that synthesizes, stores, and …
Varying Modes of Selection Among Toxin Families in the Venoms of the Giant Desert Hairy Scorpions (Hadrurus)
Venoms are primarily believed to evolve under strong diversifying selection resulting from
persistent coevolution between predator and prey. Recent research has challenged this …
persistent coevolution between predator and prey. Recent research has challenged this …
Equipped for Sexual Stings? Male-Specific Venom Peptides in Euscorpius italicus
J Krämer, R Pommerening, R Predel - International Journal of Molecular …, 2022 - mdpi.com
In the animal kingdom, intraspecific variation occurs, for example, between populations,
different life stages, and sexes. For venomous animals, this can involve differences in their …
different life stages, and sexes. For venomous animals, this can involve differences in their …
The arylsulfatase-and phospholipase-rich venom of the plutoniumid centipede Theatops posticus
AN Lane, PD Nash, SA Ellsworth, GS Nystrom… - Toxicon, 2023 - Elsevier
Research on centipede venoms has led to the discovery of a diverse array of novel proteins
and peptides, including those with homology to previously discovered toxin families (eg …
and peptides, including those with homology to previously discovered toxin families (eg …
Selection across the three-dimensional structure of venom proteins from North American Scolopendromorph centipedes
Gene duplication followed by nucleotide differentiation is one of the simplest mechanisms to
develop new functions for genes. However, the evolutionary processes underlying the …
develop new functions for genes. However, the evolutionary processes underlying the …
De novo transcriptomic and proteomic analysis and potential toxin screening of Mesobuthus martensii samples from four different provinces
S Gao, H Liang, Z Shou, Y Yao, Y Lv, J Shang… - Journal of …, 2021 - Elsevier
Highlights•Transcriptome, proteome and bioinformatic analyses were performed on different
originated Mesobuthus martensii.•Most terms in GO and KEGG annotations were consistent …
originated Mesobuthus martensii.•Most terms in GO and KEGG annotations were consistent …
Development of an LC–MS multivariate nontargeted methodology for differential analysis of the peptide profile of Asian hornet venom (Vespa velutina nigrithorax) …
TN Le, D da Silva, C Colas, E Darrouzet, P Baril… - Analytical and …, 2020 - Springer
Insect venom is a highly complex mixture of bioactive compounds, containing proteins,
peptides, and small molecules. Environmental factors can alter the venom composition and …
peptides, and small molecules. Environmental factors can alter the venom composition and …