Ayres theories of autism and sensory integration revisited: What contemporary neuroscience has to say

E Kilroy, L Aziz-Zadeh, S Cermak - Brain sciences, 2019 - mdpi.com
Abnormal sensory-based behaviors are a defining feature of autism spectrum disorders
(ASD). Dr. A. Jean Ayres was the first occupational therapist to conceptualize Sensory …

The dopamine hypothesis of autism spectrum disorder revisited: current status and future prospects

D Pavăl, IV Micluția - Developmental neuroscience, 2021 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. Despite intensive research, its …

Oxytocin normalizes altered circuit connectivity for social rescue of the Cntnap2 knockout mouse

KY Choe, RAI Bethlehem, M Safrin, H Dong, E Salman… - Neuron, 2022 - cell.com
The neural basis of abnormal social behavior in autism spectrum disorders (ASDs) remains
incompletely understood. Here we used two complementary but independent brain-wide …

The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota

P Bermudez-Martin, JAJ Becker, N Caramello… - Microbiome, 2021 - Springer
Background Autism spectrum disorders (ASD) are associated with dysregulation of the
microbiota-gut-brain axis, changes in microbiota composition as well as in the fecal, serum …

Neurotoxicity of e-cigarettes

JA Ruszkiewicz, Z Zhang, FM Gonçalves… - Food and Chemical …, 2020 - Elsevier
It appears that electronic cigarettes (EC) are a less harmful alternative to conventional
cigarette (CC) smoking, as they generate substantially lower levels of harmful carcinogens …

Structural, functional, and molecular imaging of autism spectrum disorder

X Li, K Zhang, X He, J Zhou, C Jin, L Shen, Y Gao… - Neuroscience …, 2021 - Springer
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder
associated with both genetic and environmental risks. Neuroimaging approaches have been …

Superior Colliculus to VTA pathway controls orienting response and influences social interaction in mice

C Solié, A Contestabile, P Espinosa, S Musardo… - Nature …, 2022 - nature.com
Social behaviours characterize cooperative, mutualistic, aggressive or parental interactions
that occur among conspecifics. Although the Ventral Tegmental Area (VTA) has been …

Prenatal valproate in rodents as a tool to understand the neural underpinnings of social dysfunctions in autism spectrum disorder

AM Tartaglione, S Schiavi, G Calamandrei, V Trezza - Neuropharmacology, 2019 - Elsevier
Impairments in social interaction and verbal and non verbal communication are among the
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …

Reward-related behavioral, neurochemical and electrophysiological changes in a rat model of autism based on prenatal exposure to valproic acid

S Schiavi, D Iezzi, A Manduca, S Leone… - Frontiers in cellular …, 2019 - frontiersin.org
Prenatal exposure to the antiepileptic drug valproic acid (VPA) induces autism spectrum
disorder (ASD) in humans and autistic-like behaviors in rodents, which makes it a good …

Microbial modulation via cross-fostering prevents the effects of pervasive environmental stressors on microglia and social behavior, but not the dopamine system

CJ Smith, DN Rendina, MA Kingsbury… - Molecular …, 2023 - nature.com
Environmental toxicant exposure, including air pollution, is increasing worldwide. However,
toxicant exposures are not equitably distributed. Rather, low-income and minority …