Molecular chaperone HSP70 and key regulators of apoptosis-a review

R Roufayel, S Kadry - Current molecular medicine, 2019 - ingentaconnect.com
Identified as a molecular chaperone constitutively being synthesized due to enhanced
elevated temperature change, this heat shock protein HSP70 has shown to be intimately …

[HTML][HTML] Multimodal regulation of encystation in Giardia duodenalis revealed by deep proteomics

B Balan, SJ Emery-Corbin, JJ Sandow… - International Journal for …, 2021 - Elsevier
Cyst formation in the parasitic protist Giardia duodenalis is critical to its transmission.
Existing proteomic data quantifies only 17% of coding genes transcribed during encystation …

In vivo Validation of Hsp90 Trans-splicing in Giardia lamblia: Highlighting the Role of Cis-elements

S Tushir, P Jhanwar, M Benda, V Horáčková… - Journal of Molecular …, 2024 - Elsevier
Giardia lamblia causes giardiasis, one of the most common human infectious diseases
globally. Previous studies from our lab have shown that hsp90 gene of Giardia is split into …

[HTML][HTML] The role of nuclear organization in trans-splicing based expression of heat shock protein 90 in Giardia lamblia

V Iyer, S Tushir, S Verma, S Majumdar… - PLoS Neglected …, 2021 - journals.plos.org
Hsp90 gene of G. lamblia has a split nature comprising two ORFs separated by 777 kb on
chromosome 5. The ORFs of the split gene on chromosome 5 undergo transcription to …

Precise gene models using long-read sequencing reveal a unique poly (A) signal in Giardia lamblia

DY Bilodeau, RM Sheridan, B Balan, AR Jex… - RNA, 2022 - rnajournal.cshlp.org
During pre-mRNA processing, the poly (A) signal is recognized by a protein complex that
ensures precise cleavage and polyadenylation of the nascent transcript. The location of this …