RNAi-based therapeutics and novel RNA bioengineering technologies

GM Traber, AM Yu - Journal of Pharmacology and Experimental …, 2023 - ASPET
RNA interference (RNAi) provides researchers with a versatile means to modulate target
gene expression. The major forms of RNAi molecules, genome-derived microRNAs …

[HTML][HTML] Therapeutic advances of miRNAs: A preclinical and clinical update

C Chakraborty, AR Sharma, G Sharma… - Journal of advanced …, 2021 - Elsevier
Background miRNAs, a class of small endogenous RNAs, are one of the essential
biopharmaceuticals which are in commercial spans as next-generation medicine in recent …

Viruses in colorectal cancer

L Marongiu, H Allgayer - Molecular oncology, 2022 - Wiley Online Library
Increasing evidence suggests that microorganisms might represent at least highly
interesting cofactors in colorectal cancer (CRC) oncogenesis and progression. Still …

[HTML][HTML] LncRNA HOTAIR promotes proliferation and inhibits apoptosis by sponging miR-214-3p in HPV16 positive cervical cancer cells

Y Zhou, Y Wang, M Lin, D Wu, M Zhao - Cancer Cell International, 2021 - Springer
Background Cervical cancer (CC) is one of the most common gynaecological malignancies
all around the world. The mechanisms of cervical carcinoma formation remain under close …

[HTML][HTML] EIF4A3 induced circABCA5 promotes the gastric cancer progression by SPI1 mediated IL6/JAK2/STAT3 signaling

G Hou, H Zuo, J Shi, D Dai, H Wang… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Gastric cancer is one of the most common malignancies of the digestive system with high
mortality rates. Recent studies have demonstrated that circRNAs are novel noncoding RNAs …

[HTML][HTML] Role of virus-induced host cell epigenetic changes in cancer

V Pietropaolo, C Prezioso, U Moens - International Journal of Molecular …, 2021 - mdpi.com
The tumor viruses human T-lymphotropic virus 1 (HTLV-1), hepatitis C virus (HCV), Merkel
cell polyomavirus (MCPyV), high-risk human papillomaviruses (HR-HPVs), Epstein-Barr …

[HTML][HTML] Long intergenic non-coding RNAs in HNSCC: from “Junk DNA” to important prognostic factor

J Kozłowska, T Kolenda, P Poter, J Sobocińska… - Cancers, 2021 - mdpi.com
Simple Summary Head and neck squamous cell carcinoma (HNSCC) has one of the highest
incidence and mortality rates among all cancers. Diagnostic process and treatment results …

The potential roles of exosomal noncoding RNAs in osteosarcoma

S Li, X Wang - Journal of Cellular Physiology, 2021 - Wiley Online Library
Clinically, it is difficult to efficaciously screen and diagnose osteosarcoma (OS) in advance
due to the low sensitivity and poor specificity of the existing tumor markers. Exosomes (Exos) …

[HTML][HTML] In prostate cancer cells cytokines are early responders to gravitational changes occurring in parabolic flights

H Schulz, D Dietrichs, M Wehland, TJ Corydon… - International Journal of …, 2022 - mdpi.com
The high mortality in men with metastatic prostate cancer (PC) establishes the need for
diagnostic optimization by new biomarkers. Mindful of the effect of real microgravity on …

[HTML][HTML] Non-coding RNAs-EZH2 regulatory mechanisms in cervical cancer: The current state of knowledge

J Zheng, L Chen - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Cervical cancer (CC) is among the leading causes of death in women worldwide. Both
genetic and epigenetic regulators are required for the tumorigenesis and progression of CC …