The amyloid-β pathway in Alzheimer's disease
Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …
Advances in applying computer-aided drug design for neurodegenerative diseases
Neurodegenerative diseases (NDs) including Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and Huntington's disease are incurable and affect millions of …
amyotrophic lateral sclerosis, and Huntington's disease are incurable and affect millions of …
Subjective cognitive decline and rates of incident Alzheimer's disease and non–Alzheimer's disease dementia
RER Slot, SAM Sikkes, J Berkhof, H Brodaty… - Alzheimer's & …, 2019 - Elsevier
Introduction In this multicenter study on subjective cognitive decline (SCD) in community-
based and memory clinic settings, we assessed the (1) incidence of Alzheimer's disease …
based and memory clinic settings, we assessed the (1) incidence of Alzheimer's disease …
Diet, nutrition and the ageing brain: current evidence and new directions
Globally populations are ageing. By 2050, it is estimated that there will be two billion people
aged 60 years or over, of which 131 million are projected to be affected by dementia, while …
aged 60 years or over, of which 131 million are projected to be affected by dementia, while …
Long-term dietary flavonoid intake and subjective cognitive decline in US men and women
TS Yeh, C Yuan, A Ascherio, BA Rosner, WC Willett… - Neurology, 2021 - AAN Enterprises
Objective To prospectively examine the associations between long-term dietary flavonoids
and subjective cognitive decline (SCD). Methods We followed 49,493 women from the …
and subjective cognitive decline (SCD). Methods We followed 49,493 women from the …
Trends in dementia diagnosis rates in UK ethnic groups: analysis of UK primary care data
Objectives We compared incidence of dementia diagnosis by white, black, and Asian ethnic
groups and estimated the proportion of UK white and black people developing dementia in …
groups and estimated the proportion of UK white and black people developing dementia in …
A psychosocial goal-setting and manualised support intervention for independence in dementia (NIDUS-Family) versus goal setting and routine care: a single-masked …
Background Although national guidelines recommend that everyone with dementia receives
personalised post-diagnostic support, few do. Unlike previous interventions that improved …
personalised post-diagnostic support, few do. Unlike previous interventions that improved …
Assessment of common infections and incident dementia using UK primary and secondary care data: a historical cohort study
R Muzambi, K Bhaskaran, L Smeeth… - The Lancet Healthy …, 2021 - thelancet.com
Background Common infections have been associated with dementia risk; however,
evidence is scarce. We aimed to investigate the association between common infections …
evidence is scarce. We aimed to investigate the association between common infections …
Prevalence of and associations with agitation in residents with dementia living in care homes: MARQUE cross-sectional study
BackgroundAgitation is reportedly the most common neuropsychiatric symptom in care
home residents with dementia. AimsTo report, in a large care home survey, prevalence and …
home residents with dementia. AimsTo report, in a large care home survey, prevalence and …
[HTML][HTML] “Older Adults with ASD: The Consequences of Aging.” Insights from a series of special interest group meetings held at the International Society for Autism …
A special interest group (SIG) entitled" Older Adults with ASD: The Consequences of Aging"
was held at the International Society for Autism Research (INSAR) annual meetings in 2016 …
was held at the International Society for Autism Research (INSAR) annual meetings in 2016 …