Polymorphism of spironolactone: An unprecedented case of monotropy turning to enantiotropy with a huge difference in the melting temperatures
IB Rietveld, M Barrio, P Lloveras, R Céolin… - International journal of …, 2018 - Elsevier
Spironolactone form I melts at about 70 degrees lower than form II, which is very unusual for
two co-existing polymorphs. The phase relationships involving this unprecedented case of …
two co-existing polymorphs. The phase relationships involving this unprecedented case of …
Elucidating the dehydration mechanism of ondansetron hydrochloride dihydrate with a crystal structure
R Mizoguchi, H Uekusa - Crystal Growth & Design, 2018 - ACS Publications
In drug development, evaluating the stability of the hydrate is particularly important because
changes in the hydration state could cause alterations of the physicochemical properties. In …
changes in the hydration state could cause alterations of the physicochemical properties. In …
[PDF][PDF] 聚乙二醇6000 对间尼索地平溶解性的影响
石晓伟， 孙萌萌， 王静， 杨彩琴 - 医药导报, 2014 - yydbzz.com
摘要目的研究聚乙二醇6000 对间尼索地平溶解度和体外溶出度的影响, 为间尼索地平剂型的
选择提供参考. 方法以聚乙二醇(PEG) 6000 为载体, 采用溶剂 熔融法制备间尼索地平固体分散 …
选择提供参考. 方法以聚乙二醇(PEG) 6000 为载体, 采用溶剂 熔融法制备间尼索地平固体分散 …
An Investigation into the Polymorphism and Crystallization of Levetiracetam and the Stability of its Solid Form
Levetiracetam (LEV) crystals were prepared using different solvents at different
temperatures. The LEV crystals were systematically characterized by X-ray powder …
temperatures. The LEV crystals were systematically characterized by X-ray powder …
[PDF][PDF] Synthesis and conversion thermodynamic study of crystalline and amorphous polymorphous complexes
Y Wang, Y Xin, M Wu, C Li, W Guo - Mater Sci, 2019 - pdf.hanspub.org
Two solid forms of crystalline (CryZn) and amorphous (AmZn) complexes based on urocanic
acid and ZnSO4∙ 7H2O were prepared by different approaches. X-ray single crystal …
acid and ZnSO4∙ 7H2O were prepared by different approaches. X-ray single crystal …
Effects of m-nisoldipine on the activity and mRNA expression of four CYP isozymes in rats
Y Sun, Y Liu, X Zhang, C Wan, T Lyu, L Zhang - Xenobiotica, 2018 - Taylor & Francis
For the first time, a systemic in vivo investigation was employed to evaluate the potential
effects of m-nisoldipine on activities of rat cytochrome P450 enzymes (CYP1A2, CYP2C11 …
effects of m-nisoldipine on activities of rat cytochrome P450 enzymes (CYP1A2, CYP2C11 …
[HTML][HTML] 晶态, 无定形态同质异形配合物的合成及转化热力学研究
王雨杭， 辛雨濛， 吴梦琦， 李成勋， 郭伟 - Material Sciences, 2019 - hanspub.org
利用不同的方法制备出基于尿刊酸和ZnSO 4∙ 7H 2 O 的晶态(CryZn) 和无定形态(AmZn)
两种同质异形固体. 利用X-射线单晶衍射(XRD), X-射线粉末衍射(XRPD) …
两种同质异形固体. 利用X-射线单晶衍射(XRD), X-射线粉末衍射(XRPD) …
On the dimorphism and the pressure–temperature state diagram of racemic m-nisoldipine, a dihydropyridine calcium ion antagonist
K Li, G Gbabode, G Coquerel, R Céolin… - Annales …, 2018 - Elsevier
The pressure-temperature phase diagram of the dimorphism of racemic m-nisoldipine is
constructed using temperatures and enthalpies of fusion of forms A and B. At ordinary …
constructed using temperatures and enthalpies of fusion of forms A and B. At ordinary …
Four solid forms of tauroursodeoxycholic acid and solid-state transformations: effects of temperature and milling
K Xu, S Zheng, L Guo, S Li, L Wang, P Tang, J Yan… - RSC …, 2015 - pubs.rsc.org
Four solid forms of tauroursodeoxycholic acid (TUDCA) were investigated by X-ray
diffraction, morphological analysis, thermogravimetry, differential scanning calorimetry, and …
diffraction, morphological analysis, thermogravimetry, differential scanning calorimetry, and …
[PDF][PDF] INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACEUTICAL SCIENCES
WD Wardhani, YT Sipahutar - 2020 - pdfs.semanticscholar.org
Active pharmaceutical ingredients (API) are the main components in the
productionprocessofpharmaceuticalproducts. IftheAPIhasagoodquality, then it will lead to …
productionprocessofpharmaceuticalproducts. IftheAPIhasagoodquality, then it will lead to …