The extent of tissue regeneration varies widely between species. Mammals have a limited
regenerative capacity whilst lower vertebrates such as the zebrafish (Danio rerio), a …

Spinal cord injury is a devastating condition in which massive cell death and disruption of
neural circuitry lead to long-term chronic functional impairment and paralysis. In mammals …

Unlike adult mammals, zebrafish regenerate spinal cord tissue and recover locomotor ability
after a paralyzing injury. Here, we find that ependymal cells in zebrafish spinal cords …

Central nervous system injury re-initiates neurogenesis in anamniotes (amphibians and
fishes), but not in mammals. Activation of the innate immune system promotes regenerative …

Functionally distinct subtypes/clusters of dorsal root ganglion (DRG) neurons may play
different roles in nerve regeneration and pain. However, details about their transcriptomic …

Introduction Loss of neurons in the neural retina is a leading cause of vision loss. While
humans do not possess the capacity for retinal regeneration, zebrafish can achieve this …

The regenerative capacity of the spinal cord in mammals ends at birth. In contrast, teleost
fish and amphibians retain this capacity throughout life, leading to the use of the powerful …

Facilitating axon regeneration in the injured central nervous system remains a challenging
task. RAF-MAP2K signaling plays a key role in axon elongation during nervous system …

In fishes and salamanders, but not mammals, neural stem cells switch back to neurogenesis
after injury. The signalling environment of neural stem cells is strongly altered by the …

The human nervous system exhibits limited regenerative capabilities following damage to
the central nervous system (CNS), leading to a scarcity of effective treatments for nerve …