Obesity II: establishing causal links between chemical exposures and obesity
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …
prevailing view is that obesity results from an imbalance between energy intake and …
Obesogens: a unifying theory for the global rise in obesity
Despite varied treatment, mitigation, and prevention efforts, the global prevalence and
severity of obesity continue to worsen. Here we propose a combined model of obesity, a …
severity of obesity continue to worsen. Here we propose a combined model of obesity, a …
Does maternal low-dose cadmium exposure increase the risk of offspring to develop metabolic syndrome and/or type 2 diabetes?
Cadmium is a hazardous metal with multiple organ toxicity that causes great harm to human
health. Cadmium enters the human body through occupational exposure, diet, drinking …
health. Cadmium enters the human body through occupational exposure, diet, drinking …
Obesogens: How they are identified and molecular mechanisms underlying their action
N Mohajer, CY Du, C Checkcinco… - Frontiers in …, 2021 - frontiersin.org
Adult and childhood obesity have reached pandemic level proportions. The idea that caloric
excess and insufficient levels of physical activity leads to obesity is a commonly accepted …
excess and insufficient levels of physical activity leads to obesity is a commonly accepted …
DNA hydroxymethylation reprogramming of β-oxidation genes mediates early-life arsenic-evoked hepatic lipid accumulation in adult mice
YP Song, JW Lv, Y Zhao, X Chen, ZC Zhang… - Journal of Hazardous …, 2022 - Elsevier
The metabolic disorders are becoming an epidemic disease endangering public health in
countries. Environmental factors are mainly reason for the growth of metabolic disorders …
countries. Environmental factors are mainly reason for the growth of metabolic disorders …
Early‐Life Exposure to Low‐Dose Cadmium Accelerates Diethylnitrosamine and Diet‐Induced Liver Cancer
H Men, JL Young, W Zhou, H Zhang… - Oxidative medicine …, 2021 - Wiley Online Library
Maternal exposure to cadmium causes obesity and metabolic changes in the offspring,
including nonalcoholic fatty liver disease‐like pathology. However, whether maternal …
including nonalcoholic fatty liver disease‐like pathology. However, whether maternal …
Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction
MD Simmers, KM Hudson, M Baptissart, M Cowley - Epigenetics, 2023 - Taylor & Francis
Cadmium (Cd) is a toxic metal ubiquitous in the environment. In utero, Cd is inefficiently
transported to the foetus but causes foetal growth restriction (FGR), likely through …
transported to the foetus but causes foetal growth restriction (FGR), likely through …
Developmental exposure to endocrine disrupting chemicals and its impact on cardio-metabolic-renal health
Developmental origin of health and disease postulates that the footprints of early life
exposure are followed as an endowment of risk for adult diseases. Epidemiological and …
exposure are followed as an endowment of risk for adult diseases. Epidemiological and …
The imprinted gene Zac1 regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease
SD Riegl, C Starnes, DD Jima, M Baptissart… - Toxicological …, 2023 - academic.oup.com
Cadmium (Cd) exposure in adulthood is associated with nonalcoholic fatty liver disease
(NAFLD), characterized by steatosis, inflammation, and fibrosis. The prevalence of NAFLD in …
(NAFLD), characterized by steatosis, inflammation, and fibrosis. The prevalence of NAFLD in …
Associations of Prenatal First Trimester Essential and Nonessential Metal Mixtures with Body Size and Adiposity in Childhood.
Background: Prenatal nonessential metals may contribute to postnatal adiposity, whereas
essential metals may have metabolic benefits. We evaluated joint and individual …
essential metals may have metabolic benefits. We evaluated joint and individual …