Cells of the tumor microenvironment speak the Wnt language

VL Katanaev, A Baldin, TV Denisenko… - Trends in Molecular …, 2023 - cell.com
Wnt signaling plays numerous functions in cancer, from primary transformation and tumor
growth to metastasis. In addition to these cancer cell-intrinsic functions, Wnt signaling …

[HTML][HTML] Unveiling the contribution of tumor-associated macrophages in driving epithelial-mesenchymal transition: a review of mechanisms and therapeutic Strategies

Y Zhang, X Ding, X Zhang, Y Li, R Xu, HJ Li… - Frontiers in …, 2024 - frontiersin.org
Tumor-associated macrophages (TAMs), fundamental constituents of the tumor
microenvironment (TME), significantly influence cancer development, primarily by promoting …

Targeting β-catenin using XAV939 nanoparticle promotes immunogenic cell death and suppresses conjunctival melanoma progression

F Antony, X Kang, C Pundkar, C Wang, A Mishra… - International journal of …, 2023 - Elsevier
Many tumors dysregulate Wnt/β-catenin pathway to promote stem-cell-like phenotype,
tumorigenesis, immunosuppression, and resistance to targeted cancer immunotherapies …

WNT9A Affects Late-Onset Acute Respiratory Distress Syndrome and 28-Day Survival: Evidence from a Three-Step Multiomics Study

J Chen, J Tang, M Nie, Y Li, MM Wurfel… - American Journal of …, 2023 - atsjournals.org
Late-onset (more than 48 h after ICU admission) acute respiratory distress syndrome
(ARDS) is associated with shorter survival time and higher mortality; however, the …

FOXK1 upregulation is correlated with tumor progression and tumor associated macrophages infiltration in renal cell carcinoma

S Chen, X Pan, L Zhang, X Cui… - Molecular …, 2024 - Wiley Online Library
Renal cell carcinoma (RCC) is one of the most common urological cancers in adults.
Forkhead box k1 (FOXK1) is a transcription factor involved in the progression of various …

CoCo-ST: Comparing and Contrasting Spatial Transcriptomics data sets using graph contrastive learning

J Wu, M Aminu, B Zhu, N Vokes, H Chen, L Hong, J Li… - 2024 - researchsquare.com
Traditional feature dimension reduction methods have been widely used to uncover
biological patterns or structures within individual spatial transcriptomics data. However …

[PDF][PDF] Influence of β-catenin inhibition on monocyte migration towards glioblastoma stem cells

JF Cornelius - docserv.uni-duesseldorf.de
Influence of β-catenin inhibition on monocyte migration towards glioblastoma stem cells Page 1
Aus der Klinik für Neurochirurgie der Heinrich-Heine-Universität Düsseldorf Kommissarischer …