Anticoagulant drugs antagonize coagulation and are used to prevent or cure (recurrent)
venous thromboembolism (VTE). Drugs to prevent clotting have been used for more than a …

Snake venoms are heterogeneous mixtures of proteins and peptides used for prey
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …

The carnivorous mushroom Pleurotus ostreatus uses an unknown toxin to rapidly paralyze
and kill nematode prey upon contact. We report that small lollipop-shaped structures …

CC and CXC-chemokines are the primary drivers of chemotaxis in inflammation, but
chemokine network redundancy thwarts pharmacological intervention. Tick evasins …

Antimicrobial cationic peptides are intriguing and propitious antibiotics for the future, even
against multidrug-resistant superbugs. Venoms serve as a source of cutting-edge …

Snake venom-secreted phospholipase A2 (svPLA2) enzymes, both catalytically active and
inactive, are a central component in envenoming. These are responsible for disrupting the …

Snakebite envenoming represents an important Neglected Tropical Disease (NTD) that
mainly affects tropical and subtropical developing countries according to the World Health …

Cancer cells produce abnormal levels of reactive oxygen species (ROS) that contribute to
promote their malignant phenotype. In this framework, we hypothesized that the change in …

Snake envenomation is a life-threatening disease caused by the injection of venom toxins
from the venomous snake bite. Snakebite is often defined as the occupational or domestic …

Snake venom contains a cocktail of compounds dominated by proteins and peptides, which
make up the toxin. The toxin components of snake venom attack several targets in the …