[HTML][HTML] Antibiotics in the clinical pipeline as of December 2022

MS Butler, IR Henderson, RJ Capon… - The Journal of …, 2023 - nature.com
The need for new antibacterial drugs to treat the increasing global prevalence of drug-
resistant bacterial infections has clearly attracted global attention, with a range of existing …

The endocannabinoid system: a potential target for the treatment of various diseases

H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Phytocannabinoids: origins and biosynthesis

T Gülck, BL Møller - Trends in plant science, 2020 - cell.com
Phytocannabinoids are bioactive natural products found in some flowering plants, liverworts,
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …

Resistance of gram-positive bacteria to current antibacterial agents and overcoming approaches

B Jubeh, Z Breijyeh, R Karaman - Molecules, 2020 - mdpi.com
The discovery of antibiotics has created a turning point in medical interventions to
pathogenic infections, but unfortunately, each discovery was consistently followed by the …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

[HTML][HTML] The antimicrobial potential of cannabidiol

MAT Blaskovich, AM Kavanagh, AG Elliott… - Communications …, 2021 - nature.com
Antimicrobial resistance threatens the viability of modern medicine, which is largely
dependent on the successful prevention and treatment of bacterial infections. Unfortunately …

Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history

SA Bonini, M Premoli, S Tambaro, A Kumar… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Cannabis sativa L.(C. sativa) is an annual dioecious plant,
which shares its origins with the inception of the first agricultural human societies in Asia …

Minor cannabinoids: biosynthesis, molecular pharmacology and potential therapeutic uses

KB Walsh, AE McKinney, AE Holmes - Frontiers in Pharmacology, 2021 - frontiersin.org
The medicinal use of Cannabis sativa L. can be traced back thousands of years to ancient
China and Egypt. While marijuana has recently shown promise in managing chronic pain …

Cannabis sativa: The Plant of the Thousand and One Molecules

CM Andre, JF Hausman, G Guerriero - Frontiers in plant science, 2016 - frontiersin.org
Cannabis sativa L. is an important herbaceous species originating from Central Asia, which
has been used in folk medicine and as a source of textile fiber since the dawn of times. This …

Phytocannabinoids: a unified critical inventory

LO Hanuš, SM Meyer, E Muñoz… - Natural product …, 2016 - pubs.rsc.org
Covering up to January 2016 Cannabis sativa L. is a prolific, but not exclusive, producer of a
diverse group of isoprenylated resorcinyl polyketides collectively known as …