Neurocognitive functioning in individuals at clinical high risk for psychosis: a systematic review and meta-analysis

A Catalan, GS De Pablo, C Aymerich, S Damiani… - JAMA …, 2021 - jamanetwork.com
Importance Neurocognitive functioning is a potential biomarker to advance detection,
prognosis, and preventive care for individuals at clinical high risk for psychosis (CHR-P) …

European Psychiatric Association guidance on assessment of cognitive impairment in schizophrenia

A Vita, W Gaebel, A Mucci, G Sachs, A Erfurth… - European …, 2022 - cambridge.org
Background Impairment in a wide range of cognitive abilities has been consistently reported
in individuals with schizophrenia. Both neurocognitive and social cognitive deficits are …

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

G Davies, M Lam, SE Harris, JW Trampush… - Nature …, 2018 - nature.com
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

Cognitive impairment in psychotic illness: prevalence, profile of impairment, developmental course, and treatment considerations

A McCleery, KH Nuechterlein - Dialogues in clinical neuroscience, 2019 - Taylor & Francis
Despite effective pharmacological treatments for psychotic symptoms (eg, hallucinations,
delusions), functional outcomes for people with psychotic disorders are often disappointing …

The global cognitive impairment in schizophrenia: consistent over decades and around the world

J Schaefer, E Giangrande, DR Weinberger… - Schizophrenia …, 2013 - Elsevier
Objective Schizophrenia results in cognitive impairments as well as positive, negative, and
disorganized symptomatology. The present study examines the extent to which these …

Factors associated with real-life functioning in persons with schizophrenia in a 4-year follow-up study of the Italian network for research on psychoses

A Mucci, S Galderisi, D Gibertoni, A Rossi… - JAMA …, 2021 - jamanetwork.com
Importance The goal of schizophrenia treatment has shifted from symptom reduction and
relapse prevention to functional recovery; however, recovery rates remain low. Prospective …

The influence of illness‐related variables, personal resources and context‐related factors on real‐life functioning of people with schizophrenia

S Galderisi, A Rossi, P Rocca, A Bertolino… - World …, 2014 - Wiley Online Library
In people suffering from schizophrenia, major areas of everyday life are impaired, including
independent living, productive activities and social relationships. Enhanced understanding …

Interplay among psychopathologic variables, personal resources, context-related factors, and real-life functioning in individuals with schizophrenia: a network analysis

S Galderisi, P Rucci, B Kirkpatrick, A Mucci… - JAMA …, 2018 - jamanetwork.com
Importance Enhanced understanding of factors associated with symptomatic and functional
recovery is instrumental to designing personalized treatment plans for people with …

Antipsychotic Drugs and Cognitive Function: A Systematic Review and Pairwise Network Meta-Analysis

L Feber, NL Peter, V Chiocchia… - Jama …, 2024 - jamanetwork.com
Importance Cognitive deficits are a substantial part of the symptoms of schizophrenia
spectrum disorders (SSDs) and contribute heavily to the burden of disease. Antipsychotic …

Association of neurocognition with transition to psychosis: baseline functioning in the second phase of the North American Prodrome Longitudinal Study

LJ Seidman, DI Shapiro, WS Stone… - JAMA …, 2016 - jamanetwork.com
Importance Neurocognition is a central characteristic of schizophrenia and other psychotic
disorders. Identifying the pattern and severity of neurocognitive functioning during the “near …