Patients with diabetic nephropathy have a higher risk of mortality, mostly from cardiovascular
complications. Standard biomarkers including serum creatinine, estimated glomerular …

The Monocyte chemoattractant protein-1 (MCP-1), also referred to as chemokine ligand 2
(CCL2), belongs to the extensive chemokine family and serves as a crucial mediator of …

Background Improvement of proteinuria as a marker for disease activity is associated with a
better renal outcome in immunoglobulin A nephropathy (IgAN). Complement is an effector …

IgA nephropathy (IgAN) features variable renal pathology and a heterogeneous clinical
course. Our aim was to search noninvasive biomarkers from urinary exosomes for IgAN …

Background Increased monocyte chemoattractant protein-1 (MCP-1) and decreased
epidermal growth factor (EGF) are promising biomarkers to predict progressive decline in …

BACKGROUND Assessment of chronic kidney disease (CKD) risk after acute kidney injury
(AKI) is based on limited markers primarily reflecting glomerular function. We evaluated …

La nefropatía diabética (ND) es un problema de salud pública cuya prevalencia se
encuentra en continuo incremento, representa una importante carga económica, social y de …

Biomarkers of tubular function such as epidermal growth factor (EGF) may improve
prognostication of participants at highest risk for chronic kidney disease (CKD) after …

Background: The epidermal growth factor (EGF) is a globular protein that is generated in the
kidney, especially in the loop of Henle and the distal convoluted tubule. While EGF is …

Pericytes have been identified as a major source of myofibroblasts in renal interstitial fibrosis
(RIF). The overactivation of several signaling pathways, mainly the TGF-β and PDGF …