Efficient gene therapy is mainly dependent on the gene transfer capability of gene delivery
vectors. Non-viral vectors have become the research interest of many researchers because …

Transfection is a process by which oligonucleotides (DNA or RNA) are delivered into living
cells. This allows the synthesis of target proteins as well as their inhibition (gene silencing) …

Self-assembled synthetic gene delivery systems represent the bottom-up approach to gene
delivery and gene silencing, in which scientists are designing novel cationic and procationic …

Lipopolyplexes (LPDs) are of considerable interest for use as gene delivery vehicles. Here
LPDs have been prepared from cationic vesicles (composed of a 1: 1 molar ratio of DOTMA …

We have demonstrated that the metal complexes of polybenzimidazoles are emerging likely
as a new type of gene-delivery systems based on their strong DNA-condensing ability …

Despite decades of research in the epidermal growth factor receptor (EGFR) signalling field,
and many targeted anti-cancer drugs that have been tested clinically, the success rate for …

The Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials presents
new and selected content from the 11-volume Biomedical Polymers and Polymeric …

Lipoplexes (LDs) have been prepared from DNA and positively charged vesicles composed
of the helper lipid, dioleoyl L-α-phosphatidylethanolamine (DOPE) and either a dichain (DC) …

The design, synthesis and formulation of non‐viral gene delivery vectors is an area of
renewed research interest. Amongst the most efficient non‐viral gene delivery systems are …

Cationic peptide sequences, whether linear, branched, or dendritic, are widely used to
condense and protect DNA in both polyplex and lipopolyplex gene delivery vectors. How …