Environmental influences on the epigenome: exposure-associated DNA methylation in human populations
EM Martin, RC Fry - Annual review of public health, 2018 - annualreviews.org
DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …
environmental exposures. To date, numerous studies have detailed the manner by which …
Oral chromium exposure and toxicity
Abstract Hexavalent chromium [Cr (VI)] is a known carcinogen when inhaled. However,
inhalational exposure to Cr (VI) affects only a small portion of the population, mainly by …
inhalational exposure to Cr (VI) affects only a small portion of the population, mainly by …
Metals and molecular carcinogenesis
Y Zhu, M Costa - Carcinogenesis, 2020 - academic.oup.com
Many metals are essential for living organisms, but at higher doses they may be toxic and
carcinogenic. Metal exposure occurs mainly in occupational settings and environmental …
carcinogenic. Metal exposure occurs mainly in occupational settings and environmental …
Environmental exposures associated with elevated risk for autism spectrum disorder may augment the burden of deleterious de novo mutations among probands
Although the full aetiology of autism spectrum disorder (ASD) is unknown, familial and twin
studies demonstrate high heritability of 60–90%, indicating a predominant role of genetics in …
studies demonstrate high heritability of 60–90%, indicating a predominant role of genetics in …
Elevated homocysteine level and folate deficiency associated with increased overall risk of carcinogenesis: meta-analysis of 83 case-control studies involving 35,758 …
D Zhang, X Wen, W Wu, Y Guo, W Cui - PloS one, 2015 - journals.plos.org
Background Results of the association of folate metabolism and carcinogenesis are
conflicting. We performed a meta-analysis to examine the effect of the interaction of serum …
conflicting. We performed a meta-analysis to examine the effect of the interaction of serum …
Incorporating epigenetic data into the risk assessment process for the toxic metals arsenic, cadmium, chromium, lead, and mercury: strategies and challenges
PD Ray, A Yosim, RC Fry - Frontiers in genetics, 2014 - frontiersin.org
Exposure to toxic metals poses a serious human health hazard based on ubiquitous
environmental presence, the extent of exposure, and the toxicity and disease states …
environmental presence, the extent of exposure, and the toxicity and disease states …
Response of transposable elements to environmental stressors
IR Miousse, MCG Chalbot, A Lumen… - … Research/Reviews in …, 2015 - Elsevier
Transposable elements (TEs) comprise a group of repetitive sequences that bring positive,
negative, as well as neutral effects to the host organism. Earlier considered as “junk DNA,” …
negative, as well as neutral effects to the host organism. Earlier considered as “junk DNA,” …
Prenatal epigenetics diets play protective roles against environmental pollution
It is thought that germ cells and preimplantation embryos during development are most
susceptible to endogenous and exogenous environmental factors because the epigenome …
susceptible to endogenous and exogenous environmental factors because the epigenome …
Global DNA methylation and oxidative stress biomarkers in workers exposed to metal oxide nanoparticles
This is the first study to assess global methylation, oxidative DNA damage, and lipid
peroxidation in workers with occupational exposure to metal oxide nanomaterials (NMs) …
peroxidation in workers with occupational exposure to metal oxide nanomaterials (NMs) …
[HTML][HTML] Chromium induced neurotoxicity by altering metabolism in zebrafish larvae
Background Recently, both trivalent chromium Cr (III) and hexavalent chromium Cr (VI) have
been reported to produce neurotoxicity. However, the underlying mechanisms of the …
been reported to produce neurotoxicity. However, the underlying mechanisms of the …