New avenues for systematically inferring cell-cell communication: through single-cell transcriptomics data

X Shao, X Lu, J Liao, H Chen, X Fan - Protein & cell, 2020 - academic.oup.com
For multicellular organisms, cell-cell communication is essential to numerous biological
processes. Drawing upon the latest development of single-cell RNA-sequencing (scRNA …

[HTML][HTML] CDH2 and CDH11 act as regulators of stem cell fate decisions

S Alimperti, ST Andreadis - Stem cell research, 2015 - Elsevier
Accumulating evidence suggests that the mechanical and biochemical signals originating
from cell–cell adhesion are critical for stem cell lineage specification. In this review, we focus …

Effects of substrate stiffness and cell-cell contact on mesenchymal stem cell differentiation

AS Mao, JW Shin, DJ Mooney - Biomaterials, 2016 - Elsevier
The mechanical properties of the microenvironment and direct contact-mediated cell-cell
interactions are two variables known to be important in the determination of stem cell …

Regulating the stemness of mesenchymal stem cells by tuning micropattern features

X Wang, T Nakamoto, I Dulińska-Molak… - Journal of Materials …, 2016 - pubs.rsc.org
There is increasing evidence that microstructures play an important role in the maintenance
of the multipotency of stem cells. However, it is not clear how micropatterns affect the …

Multiscale, hierarchically patterned topography for directing human neural stem cells into functional neurons

K Yang, H Jung, HR Lee, JS Lee, SR Kim, KY Song… - ACS …, 2014 - ACS Publications
Various biophysical and biochemical factors are important for determining the fate of neural
stem cells (NSCs). Among biophysical signals, topographical stimulation by …

Controlling differentiation of adipose-derived stem cells using combinatorial graphene hybrid-pattern arrays

TH Kim, S Shah, L Yang, PT Yin, MK Hossain… - ACS …, 2015 - ACS Publications
Control of stem cell fate by modulating biophysical cues (eg, micropatterns, nanopatterns,
elasticity and porosity of the substrates) has emerged as an attractive approach in stem cell …

[HTML][HTML] Influence of cell size on cellular uptake of gold nanoparticles

X Wang, X Hu, J Li, ACM Russe, N Kawazoe… - Biomaterials …, 2016 - pubs.rsc.org
Nanoparticles (NPs) have shown great potential for biomedical applications because of their
unique physical and structural properties. A critical aspect for their clinical applications is …

Multifunctional wettability patterns prepared by laser processing on superhydrophobic TiO 2 nanostructured surfaces

H Li, Y Lai, J Huang, Y Tang, L Yang, Z Chen… - Journal of Materials …, 2015 - pubs.rsc.org
A novel femtosecond laser patterning technique is reported to construct a three-dimensional
(3D) wettability pattern on a superhydrophobic TiO2 nanotube array (TNA) surface in one …

[HTML][HTML] Discriminating the independent influence of cell adhesion and spreading area on stem cell fate determination using micropatterned surfaces

X Wang, X Hu, I Dulińska-Molak, N Kawazoe, Y Yang… - Scientific reports, 2016 - nature.com
Adhesion and spreading are essential processes of anchorage dependent cells involved in
regulation of cell functions. Cells interact with their extracellular matrix (ECM) resulting in …

The varied influences of cell adhesion and spreading on gene transfection of mesenchymal stem cells on a micropatterned substrate

Y Wang, Y Yang, X Wang, N Kawazoe, Y Yang… - Acta Biomaterialia, 2021 - Elsevier
Transmembrane transport of exogenous genes is widely investigated because of high
demand for gene therapy. Both gene carriers and cellular conditions can affect gene …