Ethical issues in therapeutic use and research in pregnant and breastfeeding women
Pregnant or potentially pregnant women have historically been excluded from clinical trials
of new medications. However, it is increasingly recognised that it is imperative to generate …
of new medications. However, it is increasingly recognised that it is imperative to generate …
[HTML][HTML] New onset type 2 diabetes mellitus risks with integrase strand transfer inhibitors-based regimens: A systematic review and meta-analysis
VD Kajogoo, W Amogne, G Medhin - Metabolism Open, 2023 - Elsevier
Objectives The development of diabetes mellitus (DM) in patients taking integrase strand
transfer inhibitors (INSTIs) has raised concerns. It's critical because, in most guidelines …
transfer inhibitors (INSTIs) has raised concerns. It's critical because, in most guidelines …
'I fear my partner will abandon me': the intersection of late initiation of antenatal care in pregnancy and poor ART adherence among women living with HIV in South …
Background Many women in sub-Saharan Africa initiate antenatal care (ANC) late in
pregnancy, undermining optimal prevention of mother-to-child-transmission (PMTCT) of HIV …
pregnancy, undermining optimal prevention of mother-to-child-transmission (PMTCT) of HIV …
Patient experiences of switching from Efavirenz-to Dolutegravir-based antiretroviral therapy: a qualitative study in Uganda
A Twimukye, M Laker, EAL Odongpiny, F Ajok… - BMC Infectious …, 2021 - Springer
Abstract Background In 2019, the World Health Organisation (WHO) recommended
Dolutegravir (DTG) as the preferred first-line antiretroviral treatment (ART) for all persons …
Dolutegravir (DTG) as the preferred first-line antiretroviral treatment (ART) for all persons …
Drug resistance, rather than low tenofovir levels in blood or urine, is associated with tenofovir, emtricitabine, and efavirenz failure in resource-limited settings
The high cost of viral load (VL) testing limits its use for antiretroviral therapy (ART)
adherence support. A low-cost lateral flow urine tenofovir (TFV) rapid assay predicts pre …
adherence support. A low-cost lateral flow urine tenofovir (TFV) rapid assay predicts pre …
Patient experiences of sexual dysfunction after transition to dolutegravir-based HIV treatment in mid-Western Uganda: a qualitative study
Background The literature on dolutegravir (DTG)-based HIV treatment has focused on
assessing therapeutic efficacy particularly with regard to viral load suppression. However …
assessing therapeutic efficacy particularly with regard to viral load suppression. However …
Provider perspectives on the acceptability and tolerability of dolutegravir-based anti-retroviral therapy after national roll-out in Uganda: a qualitative study
Abstract Background The World Health Organization recommends dolutegravir (DTG) as the
for first-line and second-line antiretroviral therapy (ART) worldwide. However, little is known …
for first-line and second-line antiretroviral therapy (ART) worldwide. However, little is known …
Community acceptability of dolutegravir-based HIV treatment in women: a qualitative study in South Africa and Uganda
Background Despite concerns about dolutegravir use in pregnancy, most low-and middle-
income countries are accelerating the introduction of dolutegravir-based regimens into …
income countries are accelerating the introduction of dolutegravir-based regimens into …
Early treatment regimens achieve sustained virologic remission in infant macaques infected with SIV at birth
X Wang, E Vincent, S Siddiqui, K Turnbull, H Lu… - Nature …, 2022 - nature.com
Early antiretroviral therapy (ART) in HIV-infected infants generally fails to achieve a
sustained state of ART-free virologic remission, even after years of treatment. Our studies …
sustained state of ART-free virologic remission, even after years of treatment. Our studies …
Transitioning women with human immunodeficiency virus to first-line preferred regimen of tenofovir disoproxil fumarate, lamivudine, and dolutegravir in Sub-Saharan …
N Shah, A Esber, JS Cavanaugh… - Clinical Infectious …, 2023 - academic.oup.com
Abstract Background In 2019, the World Health Organization (WHO) recommended
combined tenofovir disoproxil fumarate, lamivudine, and dolutegravir (TLD) as the preferred …
combined tenofovir disoproxil fumarate, lamivudine, and dolutegravir (TLD) as the preferred …