Tear biomarkers in Alzheimer's and Parkinson's diseases, and multiple sclerosis: implications for diagnosis (systematic review)

A Król-Grzymała, E Sienkiewicz-Szłapka… - International Journal of …, 2022 - mdpi.com
Biological material is one of the most important aspects that allow for the correct diagnosis of
the disease, and tears are an interesting subject of research because of the simplicity of …

Normal‑tension glaucoma: Pathogenesis and genetics

A Trivli, I Koliarakis, C Terzidou… - Experimental and …, 2019 - spandidos-publications.com
Normal‑tension glaucoma (NTG) is a multifactorial optic neuropathy which, similar to open‑
angle glaucomas, is characterized by progressive retinal ganglion cell death and …

Smart contact lens with dual‐sensing platform for monitoring intraocular pressure and matrix metalloproteinase‐9

Y Ye, Y Ge, Q Zhang, M Yuan, Y Cai, K Li… - Advanced …, 2022 - Wiley Online Library
Contact lenses have become a popular health‐monitoring wearable device due to their
direct contact with the eyes. By integrating biosensors into contact lenses, real‐time and …

From oxidative stress to inflammation in the posterior ocular diseases: diagnosis and treatment

A Dammak, F Huete-Toral, C Carpena-Torres… - Pharmaceutics, 2021 - mdpi.com
Most irreversible blindness observed with glaucoma and retina-related ocular diseases,
including age-related macular degeneration and diabetic retinopathy, have their origin in the …

Measures of disease activity in glaucoma

Y Wu, M Szymanska, Y Hu, MI Fazal, N Jiang… - Biosensors and …, 2022 - Elsevier
Glaucoma is the leading cause of irreversible blindness globally which significantly affects
the quality of life and has a substantial economic impact. Effective detective methods are …

Matrix metalloproteinases in age-related macular degeneration (AMD)

L García-Onrubia, FJ Valentín-Bravo… - International Journal of …, 2020 - mdpi.com
Age-related macular degeneration (AMD) is a complex, multifactorial and progressive retinal
disease affecting millions of people worldwide. In developed countries, it is the leading …

Identification of tear-based protein and non-protein biomarkers: Its application in diagnosis of human diseases using biosensors

SK Nandi, D Singh, J Upadhay, N Gupta… - International Journal of …, 2021 - Elsevier
Discovery of robust, selective and specific biomarkers are important for early diagnosis and
monitor progression of human diseases. Eye being a common target for several human …

Candidate glaucoma biomarkers: From proteins to metabolites, and the pitfalls to clinical applications

AFV Cueto, L Álvarez, M García, A Álvarez-Barrios… - Biology, 2021 - mdpi.com
Simple Summary Glaucoma is a devastating eye disease causing progressive vision loss
and consequent irreversible blindness. The global prevalence of glaucoma is estimated at …

Advancements in Wearable and Implantable Intraocular Pressure Biosensors for Ophthalmology: A Comprehensive Review

KY Wu, M Mina, M Carbonneau, M Marchand, SD Tran - Micromachines, 2023 - mdpi.com
Glaucoma, marked by its intricate association with intraocular pressure (IOP), stands as a
predominant cause of non-reversible vision loss. In this review, the physiological relevance …

Solanum nigrum Toxicity and Its Neuroprotective Effect Against Retinal Ganglion Cell Death Through Modulation of Extracellular Matrix in a Glaucoma Rat Model

KS Yadav, AC Bisen, S Ishteyaque… - Journal of Ocular …, 2024 - liebertpub.com
Purpose: Glaucoma is a complex degenerative optic neuropathy characterized by loss of
retinal ganglion cells (RGCs) leading to irreversible vision loss and blindness. Solanum …