Inflammatory dermatosis is characterized by persistent inflammatory infiltration and hard
repair of diseased skin. As a member of the human innate immune cells, macrophages …

Macrophages are highly heterogeneous and exhibit a diversity of functions and phenotypes.
They can be divided into pro‐inflammatory macrophages (M1) and anti‐inflammatory …

The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is an
essential component of the human innate immune system, and is closely associated with …

Systemic sclerosis (also called scleroderma, SSc) is a chronic autoimmune disorder
characterized by excessive collagen deposition leading to skin fibrosis and various internal …

One of the problems of modern medical science is cardiovascular pathology caused by
atherosclerotic vascular lesions in patients with autoimmune rheumatic diseases (ARDs) …

Abstract Systemic sclerosis (SSc, scleroderma), is an autoimmune rheumatic disease
characterized by fibrosis of the skin and internal organs, and vasculopathy. Preventing …

Background and aim Systemic sclerosis (SSc) is an immune mediated connective tissue
disease characterized by microvascular dysfunction, aberrant immune response, and …

Macrophages, as specialized, long-lasting phagocytic cells of the innate immune system,
have garnered increasing attention due to their wide distribution and various functions. The …

Systemic sclerosis (SSc) is a rare systemic autoimmune disease of unknown etiology, which
is characterized by endothelial dysfunction, pathologic vasculopathy, and increased tissue …

Background: Investigation of the inflammatory response of immune cells is a current focus of
research on autoimmune disorders. The aim of this study was to evaluate the inflammatory …