Neutrophils in acute inflammation: current concepts and translational implications
A Margraf, CA Lowell, A Zarbock - Blood, The Journal of the …, 2022 - ashpublications.org
Modulation of neutrophil recruitment and function is crucial for targeting inflammatory cells to
sites of infection to combat invading pathogens while, at the same time, limiting host tissue …
sites of infection to combat invading pathogens while, at the same time, limiting host tissue …
Neutrophil‐T cell crosstalk and the control of the host inflammatory response
S Bert, S Nadkarni, M Perretti - Immunological reviews, 2023 - Wiley Online Library
While fundamental in their innate role in combating infection and responding to injury,
neutrophils are emerging as key modulators of adaptive immune responses. Such functions …
neutrophils are emerging as key modulators of adaptive immune responses. Such functions …
Glioblastoma induces the recruitment and differentiation of dendritic-like “hybrid” neutrophils from skull bone marrow
Tumor-associated neutrophil (TAN) effects on glioblastoma (GBM) biology remain under-
characterized. We show here that neutrophils with dendritic features—including …
characterized. We show here that neutrophils with dendritic features—including …
Neutrophils in pregnancy: New insights into innate and adaptive immune regulation
S Bert, EJ Ward, S Nadkarni - Immunology, 2021 - Wiley Online Library
The immunology of pregnancy has been the focus of many studies to better understand how
the mother is able to tolerate the presence of a semi‐allogeneic fetus. Far from the initial …
the mother is able to tolerate the presence of a semi‐allogeneic fetus. Far from the initial …
Tumor-mediated neutrophil polarization and therapeutic implications
S Raftopoulou, P Valadez-Cosmes, ZN Mihalic… - International Journal of …, 2022 - mdpi.com
Neutrophils are immune cells with reported phenotypic and functional plasticity. Tumor-
associated neutrophils display many roles during cancer progression. Several tumor …
associated neutrophils display many roles during cancer progression. Several tumor …
Neutrophils in inflammatory diseases: Unraveling the impact of their derived molecules and heterogeneity
B Riaz, S Sohn - Cells, 2023 - mdpi.com
Inflammatory diseases involve numerous disorders and medical conditions defined by an
insufficient level of self-tolerance. These diseases evolve over the course of a multi-step …
insufficient level of self-tolerance. These diseases evolve over the course of a multi-step …
Autonomous IL-36R signaling in neutrophils activates potent antitumor effector functions
S Roy, K Fitzgerald, A Lalani, CW Lai… - The Journal of …, 2023 - Am Soc Clin Investig
While the rapid advancement of immunotherapies has revolutionized cancer treatment, only
a small fraction of patients derive clinical benefit. Eradication of large, established tumors …
a small fraction of patients derive clinical benefit. Eradication of large, established tumors …
Differential functional responses of neutrophil subsets in severe COVID-19 patients
KR McLeish, R Shrestha, A Vashishta… - Frontiers in …, 2022 - frontiersin.org
Neutrophils play a significant role in determining disease severity following SARS-CoV-2
infection. Gene and protein expression defines several neutrophil clusters in COVID-19 …
infection. Gene and protein expression defines several neutrophil clusters in COVID-19 …
Neutrophils: Musketeers against immunotherapy
Neutrophils, the most copious leukocytes in human blood, play a critical role in
tumorigenesis, cancer progression, and immune suppression. Recently, neutrophils have …
tumorigenesis, cancer progression, and immune suppression. Recently, neutrophils have …
Neutrophils at the crossroads: unraveling the multifaceted role in the tumor microenvironment
Over the past decade, research has prominently established neutrophils as key contributors
to the intricate landscape of tumor immune biology. As polymorphonuclear granulocytes …
to the intricate landscape of tumor immune biology. As polymorphonuclear granulocytes …