This review proposes that physical inactivity could be considered a behavior selected by
evolution for resting, and also selected to be reinforcing in life-threatening situations in …

This review focuses on how blood flow to contracting skeletal muscles is regulated during
exercise in humans. The idea is that blood flow to the contracting muscles links oxygen in …

Primary aging is the progressive and inevitable process of bodily deterioration during
adulthood. In skeletal muscle, primary aging causes defective mitochondrial energetics and …

We present a review of the characterization of healthy brain aging using MRI with an
emphasis on morphology, lesions, and quantitative MR parameters. A scope review found …

SUMMARY ACSM Position Stand on The Recommended Quantity and Quality of Exercise
for Developing and Maintaining Cardiorespiratory and Muscular Fitness, and Flexibility in …

Background—The ability of older persons to function independently is dependent largely on
the maintenance of sufficient aerobic capacity and strength to perform daily activities …

Background. Many older individuals decline functionally during hospitalization, and the
deleterious consequences of bed rest may be one cause. This study reports on the effect of …

Increased life expectancy combined with the aging baby boomer generation has resulted in
an unprecedented global expansion of the elderly population. The growing population of …

Because of the influence of cardiorespiratory fitness on functional independence, quality of
life, and cardiovascular disease and all-cause mortality, tremendous interest has been …

The definition of whether and how advancing age affects cardiovascular structure and
function is a formidable research endeavor because other factors that covary with age, ie …