Therapeutic advances in multiple sclerosis
JH Yang, T Rempe, N Whitmire, A Dunn-Pirio… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system that
causes significant disability and healthcare burden. The treatment of MS has evolved over …
causes significant disability and healthcare burden. The treatment of MS has evolved over …
Multiple sclerosis in children: differential diagnosis, prognosis, and disease-modifying treatment
D Jakimovski, S Awan, SP Eckert, O Farooq… - CNS drugs, 2022 - Springer
Pediatric-onset multiple sclerosis (POMS) is a rare neuroinflammatory and
neurodegenerative disease that has a significant impact on long-term physical and cognitive …
neurodegenerative disease that has a significant impact on long-term physical and cognitive …
Aging in multiple sclerosis: from childhood to old age, etiopathogenesis, and unmet needs: a narrative review
N Capasso, E Virgilio, A Covelli, B Giovannini… - Frontiers in …, 2023 - frontiersin.org
Multiple sclerosis (MS) primarily affects adult females. However, in the last decades, rising
incidence and prevalence have been observed for demographic extremes, such as pediatric …
incidence and prevalence have been observed for demographic extremes, such as pediatric …
Pediatric multiple sclerosis: changing the trajectory of progression
D Castillo Villagrán, EA Yeh - Current Neurology and Neuroscience …, 2023 - Springer
Abstract Purpose of Review Multiple sclerosis is a chronic inflammatory disease of the
central nervous system. When seen in children and adolescents, crucial stages of brain …
central nervous system. When seen in children and adolescents, crucial stages of brain …
Pediatric multiple sclerosis
AB Kornbluh, I Kahn - Seminars in Pediatric Neurology, 2023 - Elsevier
The current diagnostic criteria for pediatric onset multiple sclerosis (POMS) are summarized,
as well as the evidence for performance of the most recent iteration of McDonald criteria in …
as well as the evidence for performance of the most recent iteration of McDonald criteria in …
Disease-modifying therapies in managing disability worsening in paediatric-onset multiple sclerosis: a longitudinal analysis of global and national registries
Background High-efficacy disease-modifying therapies have been proven to slow disability
accrual in adults with relapsing–remitting multiple sclerosis. However, their impact on …
accrual in adults with relapsing–remitting multiple sclerosis. However, their impact on …
Plasma neurofilament light chain in children with relapsing MS receiving teriflunomide or placebo: a post hoc analysis of the randomized TERIKIDS trial
Background: The phase 3 TERIKIDS study demonstrated efficacy and manageable safety for
teriflunomide versus placebo in children with relapsing multiple sclerosis (RMS). Objective …
teriflunomide versus placebo in children with relapsing multiple sclerosis (RMS). Objective …
Twenty years of subcutaneous interferon-Beta-1a for multiple sclerosis: contemporary perspectives
MS Freedman, PK Coyle, K Hellwig, B Singer… - Neurology and …, 2024 - Springer
Multiple sclerosis (MS) is a chronic, progressive, inflammatory disorder of the central
nervous system. Relapsing–remitting MS (RRMS), the most common form of the disease, is …
nervous system. Relapsing–remitting MS (RRMS), the most common form of the disease, is …
Teriflunomide: an oral therapy for first-line treatment of children and adolescents living with relapsing-remitting multiple sclerosis
GD Costa, G Comi - Expert review of neurotherapeutics, 2023 - Taylor & Francis
Introduction Different disease-modifying therapies (DMTs) have been developed to slow
down the progression of pediatric multiple sclerosis (MS). Teriflunomide is one such DMT …
down the progression of pediatric multiple sclerosis (MS). Teriflunomide is one such DMT …
First-line disease modifying treatments in pediatric-onset multiple sclerosis in Greece: therapy initiation at more advanced age is the main cause of treatment failure, in …
Objectives Long-term immunomodulatory therapy of pediatric onset-multiple sclerosis
(POMS) is based mainly on published case series and internationally agreed guidelines …
(POMS) is based mainly on published case series and internationally agreed guidelines …