Up until the mid 2000s, the capacity to generate every cell of an organism was exclusive to
embryonic stem cells. In 2006, researchers Takahashi and Yamanaka developed an …

The development of the induced pluripotent stem cells (iPSC s) technology has
revolutionized the world on the establishment of pluripotent stem cells (PSC s) across a …

Tendon injury is a common disorder of the musculoskeletal system caused by overuse or
trauma. With increasing incidence of tendon injuries, it is necessary to find an effective …

Induced pluripotent stem cells (iPSCs) are undifferentiated stem cells characterized by the
ability to differentiate into any cell type in the body. iPSCs are a relatively new and rapidly …

Tendon injuries occur commonly in horses and their repair through scar tissue formation
predisposes horses to a high rate of re-injury. Pluripotent stem cells may provide a cell …

Reasons for performing study Skin trauma in horses often leads to the development of
chronic nonhealing wounds that lack a keratinocyte cover, vital for healing. Reports in …

Pluripotent stem cells have the capacity to grow indefinitely in culture and differentiate into
derivatives of the three germ layers. These properties underpin their potential to be used in …

Limb wounds on horses are often slow to heal and are prone to developing exuberant
granulation tissue (EGT) and close primarily through epithelialization, which results in a …

Background aims Several studies report beneficial effects of autologous and allogeneic
stem cells on wound healing. However, no comparison between autologous versus …

This chapter focuses on some of the more promising adjunctive and novel therapies
developed for or adapted to the horse, based on the specific underlying characteristics that …