Perioperative neurocognitive disorders: a narrative review focusing on diagnosis, prevention, and treatment

H Kong, LM Xu, DX Wang - CNS Neuroscience & therapeutics, 2022 - Wiley Online Library
Perioperative neurocognitive disorders (NCDs) refer to neurocognitive abnormalities
detected during the perioperative periods, including preexisting cognitive impairment …

Postoperative delirium in geriatric patients with hip fractures

Y Chen, S Liang, H Wu, S Deng, F Wang… - Frontiers in aging …, 2022 - frontiersin.org
Postoperative delirium (POD) is a frequent complication in geriatric patients with hip
fractures, which is linked to poorer functional recovery, longer hospital stays, and higher …

Comparison of logistic regression and machine learning methods for predicting postoperative delirium in elderly patients: a retrospective study

Y Song, X Yang, Y Luo, C Ouyang, Y Yu… - CNS Neuroscience …, 2023 - Wiley Online Library
Aims To compare the performance of logistic regression and machine learning methods in
predicting postoperative delirium (POD) in elderly patients. Method This was a retrospective …

The association between gut microbiota and postoperative delirium in patients

Y Zhang, K Baldyga, Y Dong, W Song… - Translational …, 2023 - nature.com
Postoperative delirium is a common postoperative complication in older patients, and its
pathogenesis and biomarkers remain largely undetermined. The gut microbiota has been …

A randomised controlled trial of dexmedetomidine for delirium in adults undergoing heart valve surgery

HB Wang, Y Jia, CB Zhang, L Zhang, YN Li… - …, 2023 - Wiley Online Library
Dexmedetomidine might reduce delirium after cardiac surgery. We allocated 326
participants to an infusion of dexmedetomidine at a rate of 0.6 μg kg− 1 for 10 min and then …

Pharmacologic prophylaxis of postoperative delirium in elderly patients: A network meta-analysis of randomized controlled trials

TH Liu, YT Lin, JY Wu, PY Huang, WW Tsai… - Journal of Psychiatric …, 2025 - Elsevier
Background The high incidence and mortality rates of postoperative delirium (POD) among
elderly patients highlights the pressing need for tailored prophylactic strategies. Despite …

Anesthesia, the developing brain, and dexmedetomidine for neuroprotection

A Tsivitis, A Wang, J Murphy, A Khan, Z Jin… - Frontiers in …, 2023 - frontiersin.org
Anesthesia-induced neurotoxicity is a set of unfavorable adverse effects on central or
peripheral nervous systems associated with administration of anesthesia. Several animal …

Melatonin and its analogs for prevention of post-cardiac surgery delirium: a systematic review and meta-analysis

Y Han, Y Tian, J Wu, X Zhu, W Wang… - Frontiers in …, 2022 - frontiersin.org
Background The effectiveness of melatonin and its analogs in preventing postoperative
delirium (POD) following cardiac surgery is controversial. The purpose of this systematic …

The potential value of systemic inflammation response index on delirium after hip arthroplasty surgery in older patients: A retrospective study

W Lu, S Lin, C Wang, P Jin, J Bian - International Journal of …, 2023 - Taylor & Francis
Purpose To explore the relationship between the systemic inflammation response index
(SIRI) and postoperative delirium (POD) in older patients with hip arthroplasty surgery …

Remifentanil vs. dexmedetomidine for cardiac surgery patients with noninvasive ventilation intolerance: a multicenter randomized controlled trial

G Hao, J Wu, S Yu, K Liu, Y Xue, Q Gong, R Xie… - Journal of Intensive …, 2024 - Springer
Background The optimal sedative regime for noninvasive ventilation (NIV) intolerance
remains uncertain. The present study aimed to assess the efficacy and safety of remifentanil …