An update on diagnostic and prognostic biomarkers for traumatic brain injury

KK Wang, Z Yang, T Zhu, Y Shi… - Expert review of …, 2018 - Taylor & Francis
Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …

Implication of cerebral astrocytes in major depression: a review of fine neuroanatomical evidence in humans

LA O'Leary, N Mechawar - Glia, 2021 - Wiley Online Library
Postmortem investigations have implicated astrocytes in many neurological and psychiatric
conditions. Multiple brain regions from individuals with major depressive disorder (MDD) …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

GFAP and S100B: what you always wanted to know and never dared to ask

D Janigro, S Mondello, JP Posti, J Unden - Frontiers in neurology, 2022 - frontiersin.org
Traumatic brain injury (TBI) is a major global health issue, with outcomes spanning from
intracranial bleeding, debilitating sequelae, and invalidity with consequences for individuals …

Biomarkers of delirium duration and delirium severity in the ICU

BA Khan, AJ Perkins, NK Prasad, A Shekhar… - Critical care …, 2020 - journals.lww.com
Objectives: Both delirium duration and delirium severity are associated with adverse patient
outcomes. Serum biomarkers associated with delirium duration and delirium severity in ICU …

Early CSF and serum S100B concentrations for outcome prediction in traumatic brain injury and subarachnoid hemorrhage

I Kellermann, A Kleindienst, N Hore… - Clinical neurology and …, 2016 - Elsevier
Objectives S100B has been proposed as a putative biochemical marker in determining the
extent of brain injury and corresponding prognosis in neurotrauma. The aim of this study …

Sex differences in traumatic brain injury: a multi-dimensional exploration in genes, hormones, cells, individuals, and society

C Ma, X Wu, X Shen, Y Yang, Z Chen, X Sun… - Chinese neurosurgical …, 2019 - Springer
Traumatic brain injury (TBI) is exceptionally prevalent in society and often imposes a
massive burden on patients' families and poor prognosis. The evidence reviewed here …

S100B and Neuron-Specific Enolase as mortality predictors in patients with severe traumatic brain injury

A Rodríguez-Rodríguez, JJ Egea-Guerrero… - Neurological …, 2016 - Taylor & Francis
Objective: To determine temporal profile and prognostic ability of S100B protein and neuron-
specific enolase (NSE) for prediction of short/long-term mortality in patients suffering from …

The Australian Traumatic Brain Injury Initiative: systematic review of predictive value of biological markers for people with moderate-severe traumatic brain injury

MK Bagg, SC Hellewell, J Keeves… - Journal of …, 2024 - liebertpub.com
The Australian Traumatic Brain Injury Initiative (AUS-TBI) aims to co-design a data resource
to predict outcomes for people with moderate-severe traumatic brain injury (TBI) across …

Association between S100B levels and long-term outcome after aneurysmal subarachnoid hemorrhage: systematic review and pooled analysis

PMR Lai, R Du - PLoS One, 2016 - journals.plos.org
S100 calcium binding protein B (S100B), a well-studied marker for neurologic injury, has
been suggested as a candidate for predicting outcome after subarachnoid hemorrhage. We …