EANM dosimetry committee series on standard operational procedures: a unified methodology for 99mTc-MAA pre- and 90Y peri-therapy dosimetry in liver radioembolization …

C Chiesa, K Sjogreen-Gleisner, S Walrand, L Strigari… - EJNMMI physics, 2021 - Springer
The aim of this standard operational procedure is to standardize the methodology employed
for the evaluation of pre-and post-treatment absorbed dose calculations in 90 Y microsphere …

Somatostatin receptor targeted PET-imaging for diagnosis, radiotherapy planning and theranostics of meningiomas: a systematic review of the literature

L Filippi, I Palumbo, O Bagni, O Schillaci, C Aristei… - Diagnostics, 2022 - mdpi.com
The aims of the present systematic review are to:(1) assess the diagnostic performance of
somatostatin receptor (SSR) targeted positron emission tomography (PET) with different …

Microspheres as a carrier system for therapeutic embolization procedures: Achievements and advances

MM Welling, N Duszenko, MP van Meerbeek… - Journal of Clinical …, 2023 - mdpi.com
The targeted delivery of anti-cancer drugs and isotopes is one of the most pursued goals in
anti-cancer therapy. One of the prime examples of such an application is the intra-arterial …

[HTML][HTML] Time-activity data fitting in molecular radiotherapy: methodology and pitfalls

OV Ivashchenko, J O'Doherty, D Hardiansyah… - Physica Medica, 2024 - Elsevier
Absorbed radiation doses are essential in assessing the effects, eg safety and efficacy, of
radiopharmaceutical therapy (RPT). Patient-specific absorbed dose calculations in the target …

99mTc-macroaggregated albumin SPECT/CT predictive dosimetry and dose-response relationship in uveal melanoma liver metastases treated with first-line selective …

F Tabotta, S Gnesin, V Dunet, A Ponti, A Digklia… - Scientific Reports, 2023 - nature.com
First-line selective internal radiation therapy (SIRT) showed promising outcomes in patients
with uveal melanoma liver metastases (UMLM). Patient survival depends on liver's disease …

Advanced radionuclides in diagnosis and therapy for hepatocellular carcinoma

H Chen, M Teng, H Zhang, X Liang, H Cheng… - Chinese Chemical …, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver,
but early diagnosis and effective treatment are still difficult. With the development of …

PET/CT with 18F-choline or 18F-FDG in Hepatocellular Carcinoma Submitted to 90Y-TARE: A Real-World Study

L Filippi, O Bagni, E Notarianni, A Saltarelli, C Ambrogi… - Biomedicines, 2022 - mdpi.com
Our aim was to assess the role of positron emission computed tomography (PET/CT) with
18F-choline (18F-FCH) or 18F-fluorodeoxyglucose (18F-FDG) in hepatocellular carcinoma …

DNA damage repair defects and targeted radionuclide therapies for prostate cancer: does mutation really matter? A systematic review

L Filippi, B Palumbo, O Bagni, V Frantellizzi… - Life, 2022 - mdpi.com
The aim of the present review was to assess the impact of DNA damage repair (DDR)
mutations on response and outcome of patients (pts) affected by advanced prostate cancer …

Integrated use of 90Y-labeled microspheres and immune checkpoint inhibitors in hepatic tumors: current status and future directions

L Filippi, L Evangelista, O Schillaci - Expert Review of …, 2023 - Taylor & Francis
Introduction Transarterial radioembolization (TARE) with yttrium-90 (90Y)-labeled
microspheres and immune check-point inhibitors (ICIs) have been successfully applied for …

Up-to-date optimization of the 90Y-PET/CT reconstruction protocol for volumetric quantification in trans-arterial radioembolization (TARE) procedures in the era of …

A Capotosti, R Moretti, A Milano, M Nardini… - Applied Sciences, 2022 - mdpi.com
(1) Background: New generation of PET-CT scanners allows performing volumetric
dosimetry based on 90Y-activity distribution. The aim of this study was to perform an up-to …