The function of biological tissues in health and disease is regulated at cellular level and is
highly influenced by the physical microenvironment, through the interaction of forces …

Combined pre−/postcapillary pulmonary hypertension (Cpc‐PH), a complication of left heart
failure, is associated with higher mortality rates than isolated postcapillary pulmonary …

SGLT-2i's exert direct anti-inflammatory and anti-oxidative effects on resting endothelial
cells. However, endothelial cells are constantly exposed to mechanical forces such as cyclic …

The mechanical behavior of tissues at the macroscale is tightly coupled to cellular activity at
the microscale. Dermal wound healing is a prominent example of a complex system in which …

Endothelial cells play a crucial role in the arterial homeostasis. In addition to physiological
risk factors, abnormal levels of hemodynamic parameters induced by the pulsatile flow …

Substantial progress has been made in the management of pulmonary arterial hypertension
(PAH) in the past 25 years, but the disease remains life-limiting. Established therapies for …

Endothelial cells are constantly exposed to mechanical stimuli, of which mechanical stretch
has shown various beneficial or deleterious effects depending on whether loads are within …

We evaluated the effects of titanium plasma nitriding and oxidation on live endothelial cell
viscoelasticity. For this, mechanically polished titanium surfaces and two surfaces treated by …

The physical cues of tumor microenvironment (TME) contribute greatly to the initiation and
progression of cancer. Tumor tissues usually become stiffer than healthy tissues with more …

Cardiovascular diseases (CVDs) are by far the leading cause of death around the world. In
2015 CVDs were responsible for 31% of all global deaths, representing a total of estimated …