[HTML][HTML] Miniaturizing chemistry and biology using droplets in open systems

Y Zeng, JW Khor, TL van Neel, W Tu… - Nature Reviews …, 2023 - nature.com
Open droplet microfluidic systems manipulate droplets on the picolitre-to-microlitre scale in
an open environment. They combine the compartmentalization and control offered by …

[HTML][HTML] Droplet-based microfluidics: applications in pharmaceuticals

TND Trinh, HDK Do, NN Nam, TT Dan, KTL Trinh… - Pharmaceuticals, 2023 - mdpi.com
Droplet-based microfluidics offer great opportunities for applications in various fields, such
as diagnostics, food sciences, and drug discovery. A droplet provides an isolated …

Recent advances in microfluidic technologies for organ-on-a-chip

C Tian, Q Tu, W Liu, J Wang - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
Abstract Organ-on-a-chip (OOC) systems were developed by combining microfluidic
technologies and tissue engineering to mimic physiological conditions in the body. OOC …

[HTML][HTML] Open microfluidics: droplet microarrays as next generation multiwell plates for high throughput screening

R Strutt, B Xiong, VF Abegg, PS Dittrich - Lab on a Chip, 2024 - pubs.rsc.org
Multiwell plates are prominent in the biological and chemical sciences; however, they face
limitations in terms of throughput and deployment in emerging bioengineering fields. Droplet …

Hybrid Biofabrication of Heterogeneous 3D Constructs Using Low-Viscosity Bioinks

SJ Kim, G Lee, JK Park - ACS Applied Materials & Interfaces, 2023 - ACS Publications
The application of cytocompatible hydrogels supporting extensive cellular activities to three-
dimensional (3D) bioprinting is crucial for recreating complex physiological environments …

Encoding Coacervate Droplets with Paramagnetism for Dynamical Reconfigurability and Spatial Addressability

Y Huang, J Huang, W Yin, F Xie, B Coleman, Y Cao… - ACS …, 2023 - ACS Publications
It is an ongoing endeavor in chemistry and materials science to regulate coacervate droplets
on a physiologically relevant spatiotemporal scale to ultimately match or even surpass living …

Bioprinted Multi‐Composition Array Mimicking Tumor Microenvironments to Evaluate Drug Efficacy with Multivariable Analysis

G Lee, SJ Kim, JK Park - Advanced Healthcare Materials, 2024 - Wiley Online Library
Current organ‐on‐a‐chip technologies confront limitations in effectively recapitulating the
intricate in vivo microenvironments and accommodating diverse experimental conditions on …

A petri-dish with micromolded pattern as a coordinate indicator for live-cell time lapse microscopy

K Yun, D Park, M Kang, J Song, Y Chung, H Bang… - BioChip Journal, 2022 - Springer
Determining the position of cells in a microscope image is essential in investigating cell
behaviors such as migration and differentiation. When observing cells over a time period …

Microswimmer Combing: Controlling Interfacial Dynamics for Open‐Surface Multifunctional Screening of Small Animals

G Sun, CA Manning, GH Lee… - Advanced healthcare …, 2021 - Wiley Online Library
Image‐based screening of multicellular model organisms is critical for both investigating
fundamental biology and drug development. Current microfluidic techniques for high …

In Vitro Cell Migration through Three-Dimensional Interfaces of Varying Depths, Widths, and Curvatures on Micropatterned Polymer Surfaces

X Wang, H Wang, F He, J Zhang - ACS Applied Bio Materials, 2020 - ACS Publications
Understanding how the injury morphology impacts endothelial repair is pivotal to curing
vascular diseases. However, animal study or traditional two-dimensional wound healing …