Increased cell proliferation as a key event in chemical carcinogenesis: application in an integrated approach for the testing and assessment of non-genotoxic …
In contrast to genotoxic carcinogens, there are currently no internationally agreed upon
regulatory tools for identifying non-genotoxic carcinogens of human relevance. The rodent …
regulatory tools for identifying non-genotoxic carcinogens of human relevance. The rodent …
A mouse-specific model to detect genes under selection in tumors
Simple Summary We introduce GUST-mouse (Genes Under Selection in Tumors for mouse),
a novel computational method designed to identify cancer driver genes within mouse tumor …
a novel computational method designed to identify cancer driver genes within mouse tumor …
[PDF][PDF] Machine learning and large scale cancer omic data: decoding the biological mechanisms underpinning cancer
V Fanfani - 2022 - core.ac.uk
Many of the mechanisms underpinning cancer risk and tumorigenesis are still not fully
understood. However, the next-generation sequencing revolution and the rapid advances in …
understood. However, the next-generation sequencing revolution and the rapid advances in …
SYSMut: decoding the functional significance of rare somatic mutations in cancer
Current tailored-therapy efforts in cancer are largely focused on a small number of highly
recurrently mutated driver genes but therapeutic targeting of these oncogenes remains …
recurrently mutated driver genes but therapeutic targeting of these oncogenes remains …