Protein phosphatase 1 catalytic isoforms: specificity toward interacting proteins
L Korrodi-Gregório, SLC Esteves, M Fardilha - Translational Research, 2014 - Elsevier
The coordinated and reciprocal action of serine-threonine protein kinases and protein
phosphatases produces transitory phosphorylation, a fundamental regulatory mechanism for …
phosphatases produces transitory phosphorylation, a fundamental regulatory mechanism for …
Regulating the regulator: insights into the cardiac protein phosphatase 1 interactome
Reversible phosphorylation of proteins is a delicate yet dynamic balancing act between
kinases and phosphatases, the disturbance of which underlies numerous disease …
kinases and phosphatases, the disturbance of which underlies numerous disease …
Phosphoprotein phosphatase 1 complexes in spermatogenesis
JV Silva, MJ Freitas, M Fardilha - Current molecular …, 2014 - ingentaconnect.com
The major post-translational modification in eukaryotes is protein phosphorylation which
mediates responses to signals in a myriad of cellular processes. Not surprisingly, many …
mediates responses to signals in a myriad of cellular processes. Not surprisingly, many …
The application of proteomic approaches to the study of mammalian spermatogenesis and sperm function
Spermatogenesis is the process by which terminally differentiated sperm are produced from
male germline stem cells. This complex developmental process requires the coordination of …
male germline stem cells. This complex developmental process requires the coordination of …
The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis
M Ferreira, S Boens, C Winkler, K Szekér… - Scientific Reports, 2017 - nature.com
NIPP1 is one of the major nuclear interactors of protein phosphatase PP1. The deletion of
NIPP1 in mice is early embryonic lethal, which has precluded functional studies in adult …
NIPP1 in mice is early embryonic lethal, which has precluded functional studies in adult …
How do oncoprotein mutations rewire protein–protein interaction networks?
The acquisition of mutations that activate oncogenes or inactivate tumor suppressors is a
primary feature of most cancers. Mutations that directly alter protein sequence and structure …
primary feature of most cancers. Mutations that directly alter protein sequence and structure …
The protein phosphatase isoform PP1γ1 substitutes for PP1γ2 to support spermatogenesis but not normal sperm function and fertility
T Dudiki, N Joudeh, N Sinha, S Goswami… - Biology of …, 2019 - academic.oup.com
Four isoforms of serine/threonine phosphatase type I, PP1α, PP1β, PP1γ1, and PP1γ2, are
derived from three genes. The PP1γ1 and PP1γ2 isoforms are alternately spliced transcripts …
derived from three genes. The PP1γ1 and PP1γ2 isoforms are alternately spliced transcripts …
DDOST is associated with tumor immunosuppressive microenvironment in cervical cancer
J Mei, L Pan, M Huang, D Bao, H Gao, D Wang - Discover Oncology, 2024 - Springer
Evidence has revealed that DDOST plays an important role in cancer development and
progression. However, there are no reports on functions of DDOST in cervical …
progression. However, there are no reports on functions of DDOST in cervical …
Construction and analysis of a human testis/sperm-enriched interaction network: Unraveling the PPP1CC2 interactome
Background Phosphoprotein phosphatase 1 catalytic subunit gamma 2 (PPP1CC2), a
PPP1CC tissue-specific alternative splice restricted to testicular germ cells and …
PPP1CC tissue-specific alternative splice restricted to testicular germ cells and …
[HTML][HTML] 犏牛PPP1R11基因的克隆及在睾丸中的表达规律研究
闵星宇， 杨丽雪， 于海玲， 胡宇磊， 杨满珍， 杨璐瑜… - 畜牧兽医学报, 2022 - xml-data.org
旨在克隆犏牛蛋白磷酸酶1 调节亚基11 (protein phosphatase 1 regulatory subunit 11,
PPP1R11) 基因, 分析其在不同发育阶段睾丸中的表达与定位, 为解析其在雄性生殖中的功能 …
PPP1R11) 基因, 分析其在不同发育阶段睾丸中的表达与定位, 为解析其在雄性生殖中的功能 …