[HTML][HTML] Post-treatment Lyme disease as a model for persistent symptoms in Lyme disease

AW Rebman, JN Aucott - Frontiers in medicine, 2020 - frontiersin.org
It has long been observed in clinical practice that a subset of patients with Lyme disease
report a constellation of symptoms such as fatigue, cognitive difficulties, and musculoskeletal …

The role of infections in autoimmune disease

AM Ercolini, SD Miller - Clinical & Experimental Immunology, 2009 - academic.oup.com
Autoimmunity occurs when the immune system recognizes and attacks host tissue. In
addition to genetic factors, environmental triggers (in particular viruses, bacteria and other …

The enemy within: keeping self-reactive T cells at bay in the periphery

LSK Walker, AK Abbas - Nature Reviews Immunology, 2002 - nature.com
The remarkable capacity of the mammalian immune system to coordinate deadly attacks
against numerous invading pathogens, yet turn a blind eye to self-tissues continues to …

Epitope mapping: the first step in developing epitope-based vaccines

JM Gershoni, A Roitburd-Berman, DD Siman-Tov… - BioDrugs, 2007 - Springer
Antibodies are an effective line of defense in preventing infectious diseases. Highly potent
neutralizing antibodies can intercept a virus before it attaches to its target cell and, thus …

Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry?

C Benoist, D Mathis - Nature immunology, 2001 - nature.com
Autoimmune diseases remain one of the mysteries that perplex immunologists. What makes
the immune system, which has evolved to protect an organism from foreign invaders, turn on …

ACVIM small animal consensus statement on Lyme disease in dogs: diagnosis, treatment, and prevention

MP Littman, RE Goldstein, MA Labato… - Journal of veterinary …, 2006 - Wiley Online Library
The purpose of this report is to offer a consensus opinion of ACVIM diplomates on the
diagnosis, treatment, and prevention of Borrelia burgdorferi infections in dogs (canine Lyme …

Lyme borreliosis

UR Hengge, A Tannapfel, SK Tyring… - The Lancet infectious …, 2003 - thelancet.com
Lyme borreliosis is a multi-organ infection caused by spirochetes of the Borrelia burgdorferi
sensu lato group with its species B burgdorferi sensu stricto, Borrelia garinii, and Borrelia …

How can we prevent Lyme disease?

EB Hayes, J Piesman - New England Journal of Medicine, 2003 - Mass Medical Soc
More than 75,000 cases of Lyme disease are reported each year in Europe and the United
States. Prophylactic treatment after tick bites is only one part of a plan for primary prevention …

Elucidation of Lyme arthritis

AC Steere, L Glickstein - Nature Reviews Immunology, 2004 - nature.com
Before the first description of Lyme arthritis in 1976, patients with this disease were often
thought to have juvenile or adult rheumatoid arthritis. It is now known that Lyme arthritis is …

Autoimmune diseases: genes, bugs and failed regulation

J Ermann, CG Fathman - Nature immunology, 2001 - nature.com
In this Overview, common themes of the accompanying News & Views on RA, SLE, IDDM,
thyroiditis and MS are discussed. A unifying concept for the development of these and other …