Aptamers and their biological applications

KM Song, S Lee, C Ban - Sensors, 2012 - mdpi.com
Recently, aptamers have attracted the attention of many scientists, because they not only
have all of the advantages of antibodies, but also have unique merits, such as thermal …

Functional nucleic acid sensors

J Liu, Z Cao, Y Lu - Chemical reviews, 2009 - ACS Publications
Sensors are devices that respond to physical or chemical stimuli and produce detectable
signals. 1r4 They are a critical extension of human perception of the world in many aspects …

Aptamer-based biosensors

S Song, L Wang, J Li, C Fan, J Zhao - TrAC Trends in Analytical Chemistry, 2008 - Elsevier
Nucleic-acid aptamers have attracted intense interest and found wide applications in a
range of areas. In this review, we summarize recent advances in the development of …

Aptamers: molecular tools for analytical applications

T Mairal, V Cengiz Özalp, P Lozano Sánchez… - Analytical and …, 2008 - Springer
Aptamers are artificial nucleic acid ligands, specifically generated against certain targets,
such as amino acids, drugs, proteins or other molecules. In nature they exist as a nucleic …

Aptamer biosensor based on fluorescence resonance energy transfer from upconverting phosphors to carbon nanoparticles for thrombin detection in human plasma

Y Wang, L Bao, Z Liu, DW Pang - Analytical chemistry, 2011 - ACS Publications
We presented a new aptamer biosensor for thrombin in this work, which was based on
fluorescence resonance energy transfer (FRET) from upconverting phosphors (UCPs) to …

Visual cocaine detection with gold nanoparticles and rationally engineered aptamer structures

J Zhang, L Wang, D Pan, S Song, FYC Boey, H Zhang… - small, 2008 - Wiley Online Library
A novel bioassay strategy is designed to detect small‐molecule targets such as cocaine,
potassium, and adenosine, based on gold nanoparticles (AuNPs) and engineered DNA …

Surface immobilization methods for aptamer diagnostic applications

S Balamurugan, A Obubuafo, SA Soper… - Analytical and …, 2008 - Springer
In this review we examine various methods for the immobilization of aptamers onto different
substrates that can be utilized in a diverse array of analytical formats. In most cases …

Dual-recognition molecularly imprinted aptasensor based on gold nanoparticles decorated carboxylated carbon nanotubes for highly selective and sensitive …

AM Mahmoud, SA Alkahtani, BA Alyami… - Analytica Chimica Acta, 2020 - Elsevier
In this study, an electrochemical aptamer based sensor (aptasensor) was proposed for
specific recognition of histamine (HIS). The electrochemical aptasensor based on fabrication …

Polymer thin films embedded with metal nanoparticles for electrochemical biosensors applications

S Prakash, T Chakrabarty, AK Singh… - Biosensors and …, 2013 - Elsevier
Currently, polymer thin films embedded with metal nanoparticles provided the suitable
microenvironment for biomolecules immobilization retaining their biological activity with …

Electrochemical aptasensors–recent achievements and perspectives

T Hianik, J Wang - … to Fundamental and Practical Aspects of …, 2009 - Wiley Online Library
This article reviews recent achievements in developing aptamer‐based electrochemical
biosensors (electrochemical aptasensors). Aptamers are single stranded DNA or RNA …