Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan
The traditional view of chronic obstructive pulmonary disease (COPD) as a self-inflicted
disease caused by tobacco smoking in genetically susceptible individuals has been …
disease caused by tobacco smoking in genetically susceptible individuals has been …
Asthma epidemiology and risk factors
J Stern, J Pier, AA Litonjua - Seminars in immunopathology, 2020 - Springer
Asthma is a clinical syndrome that affects all age groups. Asthma prevalence worldwide has
seen a rapid increase in the latter part of the last century. Recent data has shown that …
seen a rapid increase in the latter part of the last century. Recent data has shown that …
Impact of air pollution on asthma outcomes
AI Tiotiu, P Novakova, D Nedeva… - International journal of …, 2020 - mdpi.com
Asthma is a chronic respiratory disease characterized by variable airflow obstruction,
bronchial hyperresponsiveness, and airway inflammation. Evidence suggests that air …
bronchial hyperresponsiveness, and airway inflammation. Evidence suggests that air …
Air pollution and DNA methylation: effects of exposure in humans
CF Rider, C Carlsten - Clinical epigenetics, 2019 - Springer
Air pollution exposure is estimated to contribute to approximately seven million early deaths
every year worldwide and more than 3% of disability-adjusted life years lost. Air pollution …
every year worldwide and more than 3% of disability-adjusted life years lost. Air pollution …
Associations between outdoor air pollutants and non-viral asthma exacerbations and airway inflammatory responses in children and adolescents living in urban areas …
MC Altman, M Kattan, GT O'Connor… - The Lancet Planetary …, 2023 - thelancet.com
Background Asthma prevalence and severity have markedly increased with urbanisation,
and children in low-income urban centres have among the greatest asthma morbidity …
and children in low-income urban centres have among the greatest asthma morbidity …
DNA methylation in childhood asthma: an epigenome-wide meta-analysis
CJ Xu, C Söderhäll, M Bustamante, N Baïz… - The lancet Respiratory …, 2018 - thelancet.com
Background DNA methylation profiles associated with childhood asthma might provide
novel insights into disease pathogenesis. We did an epigenome-wide association study to …
novel insights into disease pathogenesis. We did an epigenome-wide association study to …
[HTML][HTML] Epigenome-wide meta-analysis of DNA methylation and childhood asthma
Background Epigenetic mechanisms, including methylation, can contribute to childhood
asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease …
asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease …
Epigenetics as a mechanism linking developmental exposures to long-term toxicity
A variety of experimental and epidemiological studies lend support to the Developmental
Origin of Health and Disease (DOHaD) concept. Yet, the actual mechanisms accounting for …
Origin of Health and Disease (DOHaD) concept. Yet, the actual mechanisms accounting for …
Prenatal particulate air pollution and DNA methylation in newborns: an epigenome-wide meta-analysis
Background: Prenatal exposure to air pollution has been associated with childhood
respiratory disease and other adverse outcomes. Epigenetics is a suggested link between …
respiratory disease and other adverse outcomes. Epigenetics is a suggested link between …
The impact of air pollution on skin and related disorders: a comprehensive review
As the largest organ in the body, human skin is constantly exposed to harmful compounds
existing in the surrounding environment as the first‐line barrier. Studies have indicated that …
existing in the surrounding environment as the first‐line barrier. Studies have indicated that …