Over the past two decades, single-molecule techniques have evolved into robust tools to
study many fundamental biological processes. The combination of optical tweezers with …

The past decade has seen a revolution in our understanding of how the cellular environment
is organized, where an incredible body of work has provided new insights into the role …

In this perspective article, we focus on recent developments in the theory of charge effects in
biological DNA-related systems. The electrostatic effects on different levels of DNA …

Interaction between peptides and nucleic acids is a ubiquitous process that drives many
cellular functions, such as replications, transcriptions, and translations. Recently, this …

Despite an extensive theoretical and numerical background, the translocation ratchet
mechanism, which is fundamental for the transmembrane transport of biomolecules, has …

Polymeric toroids are fascinating soft nanostructures due to their unique geometry and
properties, which have shown potential applications in the fields of nanoreactors, drug …

The HIV-1 nucleocapsid protein (NC) is a multi-functional protein necessary for viral
replication. Recent studies have demonstrated reverse transcription occurs inside the fully …

Protamine proteins dramatically condense DNA in sperm to almost crystalline packing
levels. Here, we measure the first step in the in vitro pathway, the folding of DNA into a …

DNA in sperm undergoes an extreme compaction to almost crystalline packing levels. To
produce this dense packing, DNA is dramatically reorganized in minutes by protamine …

The control of the DNA condensation process is essential for compaction of DNA in
chromatin, as well as for biological applications such as nonviral gene therapy. This review …